Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, China; Department of Ophthalmology, Xiaozhan Hospital, Tianjin, China.
Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, China; Department of Ophthalmology, Beichen Hospital, Tianjin, China.
Ann Palliat Med. 2021 Dec;10(12):12782-12788. doi: 10.21037/apm-21-3549.
Uveitis is a not uncommon potentially sight-threatening intraocular inflammatory disorder and a major cause of blindness worldwide. Early diagnosis and effective treatment are very important to reduce complications and protect vision.
In a retrospective series, we enrolled 263 (390 eyes) consecutive uveitis patients, comprising 126 males and 137 females. The clinical types of uveitis, treatment efficacy, complications and visual prognosis were evaluated by detailed clinical examination, laboratory tests and treatment observation.
There were 101 cases of panuveitis (38.4%), 85 cases of anterior uveitis (32.3%), 75 cases of posterior uveitis (28.5%), and 2 cases of intermediate uveitis (8%). There was a statistically significant difference in (I) visual acuity between the acute and recovery periods (F=13.12, P<0.05); (II) visual acuity between first-time and recurrent patients (F=9.26, P<0.05); (III) visual acuity in the affected and healthy eyes in the total, anterior and posterior uveitis groups (P<0.05); and (IV) the presence of ocular complications. There was also a statistically significant difference in the presence or absence of ocular complications between patients with initial disease and those with a recurrence of disease (F=59.51, P<0.05).
In all its varying presentations, uveitis has a great impact on visual acuity. A careful clinical history should be taken and specific laboratory tests should be performed in order to improve the diagnosis and determine the etiology, and practitioners should provide appropriate treatment to avoid ocular complications, which can further damage visual acuity.
葡萄膜炎是一种常见的潜在致盲性眼内炎症性疾病，也是全球范围内导致失明的主要原因之一。早期诊断和有效治疗对于减少并发症和保护视力非常重要。
在一项回顾性系列研究中，我们纳入了 263 例（390 只眼）连续性葡萄膜炎患者，包括 126 例男性和 137 例女性。通过详细的临床检查、实验室检查和治疗观察，评估葡萄膜炎的临床类型、治疗效果、并发症和视力预后。
全葡萄膜炎 101 例（38.4%），前葡萄膜炎 85 例（32.3%），后葡萄膜炎 75 例（28.5%），中间葡萄膜炎 2 例（8%）。（I）急性期和恢复期视力（F=13.12，P<0.05）；（II）初发与复发患者视力（F=9.26，P<0.05）；（III）总葡萄膜炎、前葡萄膜炎和后葡萄膜炎组患眼和健眼视力（P<0.05）；（IV）眼部并发症的存在存在显著差异。初发病例和复发病例的眼部并发症发生率存在显著差异（F=59.51，P<0.05）。
葡萄膜炎的各种表现都会对视力产生重大影响。临床病史应详细采集，应进行特定的实验室检查以提高诊断和确定病因，医生应提供适当的治疗以避免眼部并发症，这可能会进一步损害视力。
