Department of Hospital Management Office, Shengjing Hospital of China Medical University, Shenyang, China.
Department of Cardiology, Shengjing Hospital of China Medical University, Shenyang, China.
Ann Palliat Med. 2021 Dec;10(12):12412-12419. doi: 10.21037/apm-21-3212.
The concentration of air pollutants is affected by changes in climatic conditions. Air temperature is a main factor affecting the concentration of air pollutants. This study sought to examine the relationship between air temperature, air pollutants, and their interactions in elderly patients with coronary heart disease (CHD) in Liaoning Province, China.
The population data primarily comprised data on daily hospitalizations due to CHD between January 1, 2015 and December 31, 2019 at the Shengjing Hospital of China Medical University. A total of 25,461 patients, who were permanent residents of Liaoning Province, were included in the study. The meteorological data included data on the average daily temperature and air pollutant data of the average daily concentrations of sulfur dioxide (SO2), nitrogen dioxide (NO2), and ozone (O3) over the hospitalization period. A multiple linear regression model was constructed to analyze the relationship between meteorological factors and CHD.
The interaction between air temperature and SO2, NO2, and O3 concentrations was related to the number of daily CHD-related hospitalizations in elderly patients aged ≥65 years (P=0.0023); however, this correlation was lower than that of the interaction between SO2 and NO2 concentrations (P=0.0026). Additionally, age exerted a greater effect than air temperature and air pollutants.
The incidence of CHD in elderly patients aged ≥65 years was found to be related to the interaction of SO2 and NO2 concentrations, and the interaction of air temperature and the concentrations of SO2, NO2, and O3.
空气污染物浓度受气候变化条件的影响。气温是影响空气污染物浓度的主要因素。本研究旨在探讨中国辽宁省老年冠心病（CHD）患者空气温度、空气污染物及其相互作用之间的关系。
人群数据主要包括中国医科大学盛京医院 2015 年 1 月 1 日至 2019 年 12 月 31 日期间每日因 CHD 住院的数据。共有 25461 名常住辽宁省的患者纳入研究。气象数据包括住院期间每日平均气温和二氧化硫（SO2）、二氧化氮（NO2）和臭氧（O3）平均日浓度的空气污染数据。构建了多元线性回归模型来分析气象因素与 CHD 之间的关系。
≥65 岁老年患者的空气温度与 SO2、NO2 和 O3 浓度之间的相互作用与每日 CHD 相关住院人数有关（P=0.0023）；然而，这种相关性低于 SO2 和 NO2 浓度之间的相互作用（P=0.0026）。此外，年龄的影响大于空气温度和空气污染物。
≥65 岁老年患者 CHD 的发病率与 SO2 和 NO2 浓度的相互作用以及空气温度与 SO2、NO2 和 O3 浓度的相互作用有关。
