右心房黏液瘤作为肉芽肿性多血管炎的首发表现，与血管内皮生长因子（VEGF）和白细胞介素 6（IL-6）的可能关联：病例报告及文献复习。
Right atrial myxoma as the first manifestation of granulomatosis with polyangiitis, and a possible association with vascular endothelial growth factor (VEGF) and interleukin 6 (IL-6): a case report and review of the literature.
机构信息
Department of Nephrology, Skaraborg Hospital, Skövde, Sweden.
Department of Molecular and Clinical Medicine, Institute of Medicine, The Sahlgrenska Academy at University of Gothenburg, 41 345, Gothenburg, Sweden.
出版信息
Eur J Med Res. 2022 Jan 11;27(1):4. doi: 10.1186/s40001-022-00632-z.
BACKGROUND
Granulomatosis with polyangiitis and myxomas are rare conditions previously described to co-exist. Cardiac masses are often presumed to be myxomas rather than lesions of granulomatosis with polyangiitis.
CASE PRESENTATION
We present a review of the symptoms for the two diagnoses along with the first verified case.
CONCLUSIONS
Two possible risk factors for developing myxomas (VEGF and IL-6) are explored and discussed.
背景
肉芽肿性多血管炎和黏液瘤均较为罕见，此前曾有文献报道这两种疾病可同时存在。心脏肿块通常被认为是黏液瘤，而非肉芽肿性多血管炎的病变。
病例介绍
我们回顾了这两种诊断的症状，并报告了首例经证实的病例。
结论
探讨并讨论了导致黏液瘤形成的两个可能的危险因素（VEGF 和 IL-6）。
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