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影响老年骨科创伤死亡率的因素。

Factors Influencing Geriatric Orthopaedic Trauma Mortality.

机构信息

Penn State College of Medicine, Hershey, PA, 17033 USA.

Penn State College of Medicine, Hershey, PA, 17033 USA; Department of Orthopaedics and Rehabilitation, Penn State Hershey Medical Center, Hershey, PA, 17033 USA.

出版信息

Injury. 2022 Mar;53(3):919-924. doi: 10.1016/j.injury.2022.01.005. Epub 2022 Jan 5.

Abstract

INTRODUCTION

This study aimed to: (1) evaluate the independent risk factors related to survival and mortality and (2) predict survival in geriatric orthopaedic trauma patients admitted to our institution's ICU as a Level 1 or 2 trauma activation.

METHODS

A retrospective review was performed on patients age >60, over a 10 year period, who were involved in a multi-trauma with orthopaedic injuries. Variables evaluated include: sex, age, Injury Severity Score (ISS), mechanism of injury, number and type of orthopaedic injury, anticoagulant use, comorbidities, length of stay in intensive care unit (ICU), type of ICU, ventilator use, vasopressors use, incidence of multiple organ dysfunction syndrome (MODS), number of surgeries, and 1-month and 6-month mortality. A Kaplan-Meier estimator and Cox proportional hazards analysis were used to predict and assess survival probability.

RESULTS

174 patients were included, with an average mortality of 47.7%. Deceased patients had a significantly greater age, ISS, vasopressor usage, ICU stay, incidence of MODF, incidence of genitourinary disease, anticoagulant usage, ventilator usage, number of orthopaedic surgeries, and orthopaedic injuries. The relative risk for mortality within the first month was significantly associated with increased age, ISS, high-energy trauma, length of ICU stay, MODS, psychiatric disease, and anticoagulant use. Patients with an ISS ≤30 were significantly more likely to survive than patients with an ISS of >30. Greater age, ISS, length of ICU stay, incidence of MODS, anticoagulant, and ventilator use were significantly predictive of lower survival rates. Mechanism of injury, number of orthopaedic surgeries and orthopaedic injuries, and type of orthopaedic injury were not found to be predictive of survival.

CONCLUSIONS

An ISS >30 at admission is strongly predictive of a lower probability of survival. Genitourinary disease was associated with increased mortality. Low age, ISS, length of stay in ICU, incidence of MODS, anticoagulant use, and ventilator use, are significantly predictive of survival. Number of orthopaedic surgeries, orthopaedic injuries, and type of orthopaedic injury were not found to be predictive of survival. These indications help us to better understand factors predictive of death among geriatric orthopaedic trauma patients, and improve the way we can diagnose and care for them.

摘要

介绍

本研究旨在:(1) 评估与生存和死亡相关的独立风险因素;(2) 预测我院 ICU 收治的老年骨科创伤患者的生存率。

方法

对 10 年间多发创伤合并骨科损伤且年龄>60 岁的患者进行回顾性分析。评估的变量包括:性别、年龄、损伤严重度评分(ISS)、损伤机制、骨科损伤类型和数量、抗凝剂使用、合并症、重症监护病房(ICU)住院时间、ICU 类型、呼吸机使用、血管加压素使用、多器官功能障碍综合征(MODS)发生率、手术次数以及 1 个月和 6 个月死亡率。使用 Kaplan-Meier 估计器和 Cox 比例风险分析来预测和评估生存率。

结果

共纳入 174 例患者,平均死亡率为 47.7%。死亡患者的年龄、ISS、血管加压素使用、ICU 住院时间、MODF 发生率、泌尿生殖系统疾病发生率、抗凝剂使用、呼吸机使用、骨科手术次数和骨科损伤均显著更高。第 1 个月内死亡的相对风险与年龄增加、ISS 升高、高能创伤、ICU 住院时间延长、MODS、精神疾病和抗凝剂使用显著相关。ISS≤30 的患者生存率显著高于 ISS>30 的患者。更大的年龄、ISS、ICU 住院时间、MODS、抗凝剂和呼吸机使用显著预测生存率较低。损伤机制、骨科手术次数和骨科损伤类型与生存率无显著相关性。

结论

入院时 ISS>30 强烈预测生存率较低。泌尿生殖系统疾病与死亡率增加相关。低年龄、ISS、ICU 住院时间、MODS 发生率、抗凝剂使用和呼吸机使用显著预测生存率。骨科手术次数、骨科损伤类型和骨科损伤与生存率无显著相关性。这些指标有助于我们更好地了解老年骨科创伤患者死亡的预测因素,并改善我们对他们的诊断和护理方式。

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