Faculty of Applied Sciences, Ho Chi Minh City University of Technology and Education, Ho Chi Minh City, Viet Nam.
College of Medical and Health Science, Asia University, Taichung, Taiwan; Center for Transdisciplinary Research (CFTR), Saveetha Institute of Medical and Technical Sciences, Saveetha University, Chennai, India.
Environ Res. 2022 May 15;208:112683. doi: 10.1016/j.envres.2022.112683. Epub 2022 Jan 10.
This research was performed to evaluate the silver nanoparticles (AgNPs) fabricating potential of aqueous shoot extract of Aristolochia bracteolata and also assess the free radicals scavenging potential of synthesized AgNPs. The results obtained from this study showed that the aqueous shoot extract of A. bracteolata has the potential to synthesize the AgNPs and it was initially confirmed by color change in the reaction blend as yellow to dark brownish. Subsequently, a clear absorbance peak was found at 425 nm in UV-visible spectrum analysis. The functional groups involved in the capping and stabilization of AgNPs were confirmed by Fourier Transform-Infrared spectroscopy (FTIR) analysis and recorded about 10 sharp peaks 3688, 3401, 2980, 2370, 1948, 1642, 1480, 1280, 782, and 628 cm. The Scanning Electron Microscope (SEM) and Transmission Electron Microscope (TEM) observations revealed that the predominant shape of the AgNPs was spherical and size ranged from 41.43 to 60.51 nm. Interestingly, the green fabricated AgNPs showed significant free radicals scavenging activity and were confirmed with ferric reducing assay, 1, 1-diphenyl-2-picryl-hydrazyl (DPPH), HO radicals, and 2,2'-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) radicals scavenging activity. Thus, after a few in-vivo antioxidant studies, Aristolochia bracteolata-mediated AgNPs can be considered as an antioxidant agent.
这项研究旨在评估马兜铃科植物水提取物合成银纳米粒子（AgNPs）的潜力，并评估合成 AgNPs 的自由基清除能力。研究结果表明，马兜铃科植物水提取物具有合成 AgNPs 的潜力，这最初通过反应混合物中颜色从黄色变为深棕色来初步证实。随后，在紫外-可见光谱分析中发现了一个明显的吸收峰，位于 425nm。傅里叶变换红外光谱（FTIR）分析证实了参与 AgNPs 包覆和稳定的官能团，并记录了约 10 个尖锐峰 3688、3401、2980、2370、1948、1642、1480、1280、782 和 628cm。扫描电子显微镜（SEM）和透射电子显微镜（TEM）观察表明，AgNPs 的主要形状为球形，尺寸范围为 41.43 至 60.51nm。有趣的是，绿色合成的 AgNPs 表现出显著的自由基清除活性，并通过铁还原测定、1,1-二苯基-2-苦基肼（DPPH）、HO 自由基和 2,2'-联氮双（3-乙基苯并噻唑啉-6-磺酸）（ABTS）自由基清除活性得到证实。因此，在进行了一些体内抗氧化研究后，马兜铃科植物介导的 AgNPs 可以被认为是一种抗氧化剂。
