• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

红色区域复发性白斑的术中管理

Intraoperative Management of Recurrent Leukoplakia at Red Zone.

作者信息

Elengkumaran S, Deepak C, Sargunam A Emmanuel Dhiravia, Ravindran C, Rajan Sharada T

机构信息

Department of Oral and Maxillofacial Surgery, Sri Ramachandra Faculty of Dental Sciences, Sri Ramachandra Institute of Higher Education and Research, Chennai, India.

Department of Oral and Maxillofacial Pathology, Sri Ramachandra Faculty of Dental Sciences, Sri Ramachandra Institute of Higher Education and Research, Chennai, India.

出版信息

J Pharm Bioallied Sci. 2021 Nov;13(Suppl 2):S1744-S1746. doi: 10.4103/jpbs.jpbs_183_21. Epub 2021 Nov 10.

DOI:10.4103/jpbs.jpbs_183_21
PMID:35018068
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8687036/
Abstract

Oral leukoplakia (OL) is a potentially malignant oral disorder (PMOD) that sometimes trans-form into oral squamous cell carcinoma (OSCC). OL is one of the most frequent PMODs seen in the oral cavity. The global prevalence of OL is approximately 2.6%, with its worst prognosis of undergoing a malignant transformation. Leukoplakia is clinically divided into red zones (tongue and floor of mouth) and nonred zones (buccal mucosa, palate, and soft palate) areas. The red zone areas have more potency of transforming into malignancy. Hence, patients with red zone areas need to be followed up more frequently and treated appropriately. This case report signifies the importance of treating one such case of leukoplakia at red zone area.

摘要

口腔白斑（OL）是一种潜在恶性口腔疾病（PMOD），有时会转变为口腔鳞状细胞癌（OSCC）。OL是口腔中最常见的PMOD之一。全球OL的患病率约为2.6%，其恶变预后最差。白斑在临床上分为红色区域（舌和口底）和非红色区域（颊黏膜、硬腭和软腭）。红色区域恶变的可能性更大。因此，红色区域的患者需要更频繁地随访并接受适当治疗。本病例报告表明了治疗红色区域白斑病例的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adf5/8687036/52561e5bbb6a/JPBS-13-1744-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adf5/8687036/2c5bd7ddb3f5/JPBS-13-1744-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adf5/8687036/6975822d05b1/JPBS-13-1744-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adf5/8687036/cf6aae4a969d/JPBS-13-1744-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adf5/8687036/581a138b03e7/JPBS-13-1744-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adf5/8687036/52561e5bbb6a/JPBS-13-1744-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adf5/8687036/2c5bd7ddb3f5/JPBS-13-1744-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adf5/8687036/6975822d05b1/JPBS-13-1744-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adf5/8687036/cf6aae4a969d/JPBS-13-1744-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adf5/8687036/581a138b03e7/JPBS-13-1744-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/adf5/8687036/52561e5bbb6a/JPBS-13-1744-g005.jpg

相似文献

1
Intraoperative Management of Recurrent Leukoplakia at Red Zone.红色区域复发性白斑的术中管理
J Pharm Bioallied Sci. 2021 Nov;13(Suppl 2):S1744-S1746. doi: 10.4103/jpbs.jpbs_183_21. Epub 2021 Nov 10.
2
The combination of SMAD4 expression and histological grade of dysplasia is a better predictor for the malignant transformation of oral leukoplakia.SMAD4 表达与异型增生的组织学分级相结合是预测口腔白斑恶变的更好指标。
PLoS One. 2013 Jun 24;8(6):e66794. doi: 10.1371/journal.pone.0066794. Print 2013.
3
Oral premalignant lesions: epidemiological and clinical analysis in the northern Polish population.口腔癌前病变：波兰北部人群的流行病学和临床分析
Postepy Dermatol Alergol. 2014 Dec;31(6):341-50. doi: 10.5114/pdia.2014.40932. Epub 2014 Dec 3.
4
[Clinicopathological Study of the Resected Oral Leukoplakia Cases].[口腔白斑切除病例的临床病理研究]
Gan To Kagaku Ryoho. 2018 Dec;45(13):1970-1972.
5
Semiquantifiable angiogenesis parameters in association with the malignant transformation of oral leukoplakia.与口腔白斑恶变相关的半定量血管生成参数。
J Oral Pathol Med. 2017 Oct;46(9):710-716. doi: 10.1111/jop.12544. Epub 2017 Feb 7.
6
Clinicopathologic factors associated with malignant transformation of oral leukoplakias: a retrospective cohort study.与口腔白斑恶变相关的临床病理因素：一项回顾性队列研究。
Int J Oral Maxillofac Surg. 2021 Nov;50(11):1422-1428. doi: 10.1016/j.ijom.2021.01.012. Epub 2021 Mar 3.
7
The prevalence of oral leukoplakia in 138 patients with oral squamous cell carcinoma.138例口腔鳞状细胞癌患者中口腔白斑的患病率。
Oral Dis. 2004 Nov;10(6):346-8. doi: 10.1111/j.1601-0825.2004.01031.x.
8
Nomogram for risk prediction of malignant transformation in oral leukoplakia patients using combined biomarkers.联合生物标志物预测口腔白斑病患者恶变风险的列线图。
Oral Oncol. 2017 Sep;72:132-139. doi: 10.1016/j.oraloncology.2017.07.015. Epub 2017 Jul 20.
9
Premalignant Lesions of the Oral Mucosa口腔黏膜的癌前病变
10
Development and validation of nomogram for prediction of malignant transformation in oral leukoplakia: A large-scale cohort study.口腔白斑癌变风险预测列线图的建立与验证：一项大规模队列研究。
J Oral Pathol Med. 2019 Jul;48(6):491-498. doi: 10.1111/jop.12862. Epub 2019 May 15.

本文引用的文献

1
Malignant transformation of oral proliferative verrucous leukoplakia: a series of 48 patients with suggestions for management.口腔增殖性疣状白斑的恶性转化：48 例患者系列及治疗建议。
Int J Oral Maxillofac Surg. 2021 Jan;50(1):14-20. doi: 10.1016/j.ijom.2020.05.019. Epub 2020 Jun 23.
2
Intraoperative assessment of surgical margins of oral squamous cell carcinoma using frozen sections: a practical clinicopathological management for recurrences.使用冰冻切片对口腔鳞状细胞癌手术切缘进行术中评估：针对复发情况的实用临床病理管理方法
Biomed Res Int. 2014;2014:823968. doi: 10.1155/2014/823968. Epub 2014 Jun 24.
3
Diagnostic aids for detection of oral precancerous conditions.
口腔癌前病变检测的诊断辅助工具。
Int J Oral Sci. 2013 Jun;5(2):59-65. doi: 10.1038/ijos.2013.24. Epub 2013 Jun 7.
4
Recurrence patterns of oral leukoplakia after curative surgical resection: important factors that predict the risk of recurrence and malignancy.口腔白斑病根治性手术切除后复发模式：预测复发和恶变风险的重要因素。
J Oral Pathol Med. 2012 Oct;41(9):682-8. doi: 10.1111/j.1600-0714.2012.01167.x. Epub 2012 Jun 15.
5
Utility of frozen section in assessment of margins and neck node metastases in patients undergoing surgery for carcinoma of the tongue.冰冻切片在评估舌癌手术患者切缘及颈部淋巴结转移中的应用价值。
J Cancer Res Ther. 2012 Jan;8 Suppl 1:S100-5. doi: 10.4103/0973-1482.92222.