Lin Churong, Liu Dong, Liu Budian, Gu Jieruo
Department of Radiology, The Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.
Department of Rheumatology and Immunology, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou, People's Republic of China.
Int J Gen Med. 2022 Jan 4;15:79-86. doi: 10.2147/IJGM.S347133. eCollection 2022.
In this study, we aimed to investigate whether there was a pattern of distribution of acute and chronic lesions in the sacroiliac joints (SIJ) of patients with axial spondyloarthritis (axSpA).
A total of 96 patients diagnosed as axSpA were retrospectively included in this study. The Spondyloarthritis Research Consortium of Canada sacroiliac joint inflammation score (SIS) and structural score (SSS) were used to evaluate the acute and chronic lesions in the SIJs. Scores representing the distribution of bone marrow edema, fatty lesions and erosions were extracted respectively. By dividing the SIJs into sacral or iliac sections, upper or lower sections, anterior and posterior levels, differences of scores representing acute and chronic lesions were analyzed by Kruskal Wallis' tests.
SIS scores were not significantly different in sacral or iliac sections, in upper or lower sections, on anterior or posterior levels. SSS scores were also not significantly different in different sections, except for higher occurrence rates of erosions in the iliac sections. Post-hoc analysis showed that there was a higher erosion score in the left ilium than left sacrum, as well as in right ilium than left sacrum.
There was no specific distribution pattern of acute or chronic lesions in the SIJs in patients with axSpA. A bigger study sample was needed to confirm the distribution of erosions in sacral or iliac sections.
在本研究中，我们旨在调查轴性脊柱关节炎（axSpA）患者骶髂关节（SIJ）急慢性病变的分布模式。
本研究回顾性纳入了96例诊断为axSpA的患者。采用加拿大脊柱关节炎研究联盟骶髂关节炎症评分（SIS）和结构评分（SSS）来评估骶髂关节的急慢性病变。分别提取代表骨髓水肿、脂肪病变和侵蚀分布的评分。通过将骶髂关节分为骶骨或髂骨部分、上部或下部、前后层面，采用Kruskal Wallis检验分析代表急慢性病变的评分差异。
骶髂关节的SIS评分在骶骨或髂骨部分、上部或下部、前后层面上无显著差异。SSS评分在不同部分也无显著差异，除了髂骨部分侵蚀发生率较高。事后分析显示，左髂骨的侵蚀评分高于左骶骨，右髂骨的侵蚀评分也高于左骶骨。
axSpA患者骶髂关节急慢性病变无特定分布模式。需要更大的研究样本以确认骶骨或髂骨部分侵蚀的分布情况。
