Mahato Abhishek, Joshi Richa, Harish S, Paliwal Dharmesh
Department of Nuclear Medicine and PET-CT, Command Hospital (Central Command), Lucknow, Uttar Pradesh, India.
Department of Nuclear Medicine and Surgical Oncology, Command Hospital (Central Command), Lucknow, Uttar Pradesh, India.
World J Nucl Med. 2021 Nov 1;20(4):374-376. doi: 10.4103/wjnm.wjnm_98_21. eCollection 2021 Oct-Dec.
A 35-year-old female with a 15-week period of gestation was detected with locally advanced cancer of the left breast. She was suggested to undergo a medical termination of pregnancy (MTP) followed by invasive Oncological imaging - Contrast enhanced computed tomography (CECT) chest-abdomen-pelvis/fluorodeoxyglucose positron emission tomography-CT (FDG PET-CT) for staging the disease. However, to avoid the risk of iatrogenic novel coronavirus 2019 infection to the patient, on her request, the hospital admission was carried out after the oncological workup and thus PET-CT was conducted before the MTP. FDG PET-CT revealed FDG avid primary in the left breast along with extensive metastases to liver and skeletal lesions. The developing fetus also showed physiological FDG uptake. The patient has undergone an MTP and is presently under treatment for metastatic breast cancer. The case report illustrates the radiation safety guidelines on fetal radiation exposure, steps to decrease fetal radiation exposure, and illustration of fetal FDG uptake.
一名35岁妊娠15周的女性被检测出患有左乳局部晚期癌症。建议她先进行人工流产，然后进行侵入性肿瘤影像学检查——胸部-腹部-盆腔增强计算机断层扫描（CECT）/氟脱氧葡萄糖正电子发射断层扫描-CT（FDG PET-CT）以对疾病进行分期。然而，为避免给患者带来医源性2019新型冠状病毒感染的风险，应她的要求，在肿瘤检查后才办理住院手续，因此PET-CT在人工流产之前进行。FDG PET-CT显示左乳有FDG摄取活跃的原发灶，同时伴有肝脏和骨骼广泛转移。发育中的胎儿也显示出生理性FDG摄取。该患者已接受人工流产，目前正在接受转移性乳腺癌治疗。本病例报告阐述了胎儿辐射暴露的辐射安全指南、减少胎儿辐射暴露的措施以及胎儿FDG摄取的实例。
