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正电子发射断层显像/计算机断层扫描(PET/CT)在妊娠中的应用:一例甲状旁腺癌病例报告及文献综述

The use of PET/CT in pregnancy: A case report of malignant parathyroid carcinoma and a review of the literature.

作者信息

Gill Manpreet Mona, Sia Winnie, Hoskinson Michael, Niven Erin, Khurana Rshmi

机构信息

1Department of Medicine, University of Alberta, Edmonton, Canada.

2Department of Obstetrics and Gynecology, University of Alberta, Edmonton, Canada.

出版信息

Obstet Med. 2018 Mar;11(1):45-49. doi: 10.1177/1753495X17724950. Epub 2017 Oct 9.

Abstract

Positron emission tomography scanning is not commonly performed in pregnancy but can be done if required. Fetal doses of radiation can be minimized, and our case exemplifies the safe application of positron emission tomography/computed tomography in pregnancy. A 38-year-old woman in her first ongoing pregnancy presented at 28 weeks' gestation with symptomatic hypercalcemia. Given a history of parathyroid carcinoma, recurrence was suspected. Ultrasound and magnetic resonance imaging failed to locate the lesion. However, positron emission tomography/computed tomography identified a culprit supraclavicular lymph node. This was excised under local anesthesia resulting in normalization of parathyroid hormone and calcium levels. A term, healthy baby was delivered. The literature provides support that the use of positron emission tomography/computed tomography is acceptable when indicated, and there are modifications to protocols that can further limit risk.

摘要

正电子发射断层扫描在孕期并不常用,但如有需要也可进行。胎儿所受辐射剂量可减至最小,我们的病例例证了正电子发射断层扫描/计算机断层扫描在孕期的安全应用。一名38岁首次怀孕的女性在妊娠28周时因有症状的高钙血症前来就诊。鉴于有甲状旁腺癌病史,怀疑有复发。超声和磁共振成像未能找到病变部位。然而,正电子发射断层扫描/计算机断层扫描确定了一个锁骨上淋巴结为罪魁祸首。该淋巴结在局部麻醉下切除,甲状旁腺激素和钙水平恢复正常。随后这名女性足月产下了一个健康的婴儿。文献表明,在有指征时使用正电子发射断层扫描/计算机断层扫描是可以接受的,并且对方案进行调整可以进一步降低风险。

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Hodgkin's Disease Staging by FDG PET/CT in a Pregnant Woman.一名孕妇的霍奇金淋巴瘤FDG PET/CT分期
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18F-FDG PET in pregnancy and fetal radiation dose estimates.18F-FDG PET 在妊娠中的应用及胎儿辐射剂量估算。
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Absorbed 18F-FDG dose to the fetus during early pregnancy.早期妊娠时胎儿吸收的 18F-FDG 剂量。
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