Cardozo Lomaquiz Christian David, Frontanilla Tamara, Scavone Natalia, Fretes Alba, Torales Nathalia, Pereira María Elena, Mino de Kaspar Herminia, Ortiz Xavier, Henning Renate
DermatoCenter Clinic, Ciudad del Este, Paraguay.
School of medicine, University of São Paulo, São Paulo, Brazil.
Access Microbiol. 2021 Nov 8;3(11):000280. doi: 10.1099/acmi.0.000280. eCollection 2021.
Infections caused by fast growing mycobacteria have increased markedly worldwide. They are normally associated with trauma, surgery or cosmetic interventions. Paraguay has a deficit in sanitary control including clinics, private practices, and aesthetic centres. This situation is accompanied by the easy access to drugs, which leads to the performance of exclusively medical aesthetic procedures by people without professional knowledge or training.
A 26-year-old female patient comes to a medical consultation with pain and bruising in the abdominal area with more than 3 months of progression, without fever or apparent cause. Later, she confessed to the application of subcutaneous injections of 'growth hormones' at the gym. Excisional biopsy of the lesions was carried out for anatomopathological and microbiological studies. In addition, the use of polymerase chain reaction analysis was indicated because of the strong suspicion of an atypical mycobacterial infection. The Ziehl-Neelsen staining was negative for BAAR, and the PAS-Hematoxylin negative for fungal elements. When performing the culture, the growth of atypical mycobacteria was observed on chocolate and blood agar medium culture. Through the polymerase chain reaction study, it was possible to identify the atypical mycobacterium as .
The irresponsible application of medications by people without professional authorization or biosafety precautions can lead to the development atypical infections that are difficult to diagnose and treat. This situation could lead to serious complications and even death.
快速生长分枝杆菌引起的感染在全球范围内显著增加。它们通常与创伤、手术或美容干预有关。巴拉圭在卫生控制方面存在不足，包括诊所、私人执业机构和美容中心。这种情况伴随着药物的容易获取，导致没有专业知识或培训的人员进行单纯的医学美容程序。
一名26岁女性患者前来就医，腹部疼痛和瘀伤已持续3个多月，无发热或明显病因。后来，她承认在健身房自行皮下注射“生长激素”。对病变进行了切除活检，以进行解剖病理学和微生物学研究。此外，由于强烈怀疑是非典型分枝杆菌感染，还进行了聚合酶链反应分析。萋-尼染色BAAR为阴性，PAS-苏木精染色真菌成分阴性。进行培养时，在巧克力和血琼脂培养基培养上观察到非典型分枝杆菌生长。通过聚合酶链反应研究，可将非典型分枝杆菌鉴定为 。
未经专业授权或无生物安全预防措施的人员不负责任地用药可导致难以诊断和治疗的非典型感染。这种情况可能导致严重并发症甚至死亡。
