Department of Pediatrics, Nicklaus Children's Hospital, Miami, Florida, USA.
Division of Cardiology, Nicklaus Children's Hospital, Miami, Florida, USA.
Catheter Cardiovasc Interv. 2022 Mar;99(4):1161-1164. doi: 10.1002/ccd.30067. Epub 2022 Jan 11.
Device-related thrombosis and device-related endocarditis after atrial septal defect (ASD) transcatheter closure are extremely rare. It is known that COVID-19 infection could lead to a thrombotic microangiopathy-like phenomenon. We present the case of a 14-year-old female who developed fever and was found to have a thrombus on the right atrial side of the ASD closure device weeks after an asymptomatic COVID-19 infection and negative COVID-19 test 2 days before transcatheter ASD closure. Although there is no certainty that the thrombus was related to the prior COVID-19 infection, the possibility of an ongoing COVID-19-related hypercoagulable state should be entertained.
经导管房间隔缺损(ASD)封堵术后发生器械相关血栓形成和器械相关心内膜炎极为罕见。已知 COVID-19 感染可导致血栓性微血管病样现象。我们报告了一例 14 岁女性病例,该患者在无症状 COVID-19 感染后数周和经导管 ASD 封堵前 2 天 COVID-19 检测阴性时出现发热,并发现 ASD 封堵装置的右心房侧有血栓。尽管不能确定血栓与先前的 COVID-19 感染有关,但应考虑与持续的 COVID-19 相关高凝状态有关的可能性。