Federal Urdu University of Arts, Science, and Technology, Department of Zoology, Gulshan -e-Iqbal, Karachi, Pakistan.
Sardar Bahadur Khan Women's University, Department of Zoology, Quetta, Pakistan.
Braz J Biol. 2022 Jan 7;84:e252952. doi: 10.1590/1519-6984.252952. eCollection 2022.
The main purpose of this study was to find out a possible association between ABO blood groups or Rh and diabetes mellitus (DM) in the local population of eight (8) different towns of Karachi, Pakistan. For this purpose a survey was carried out in Karachi to have a practical observation of these towns during the period of 9 months from June 2019 to Feb. 2020. Out of eighteen (18) towns of Karachi, samples (N= 584) were collected from only eight (8) Towns of Karachi and gave a code-number to each town. Diabetic group sample was (n1=432) & pre-diabetes sample was (n2 =152). A standard Abbot Company Glucometer for Random Blood Sugar (RBS) and Fasting Blood Sugar (FBS) tests, standard blood anti sera were used for ABO/Rh blood type. Health assessment techniques were performed ethically by taking informed consent from all registered subjects. Finally data was analyzed by SPSS version 20.0. In our current study, the comparison of ABO blood groups frequencies between diabetic and pre-diabetic individuals were carried out. The percentage values of blood Group-B as given as: (32% in DM vs. 31% in pre-diabetics), followed by blood Group-O as: (18% in DM vs. 11% in pre-diabetics). Contrary to Group-"B" & "O", blood Group-A and Group-AB were distribution percentage higher pre-diabetic as compared to DM patients, as given as: Group-A (32% in pre-diabetics vs. 26% in DM) & Group-AB (26% in pre-diabetics vs. 24% in diabetic's patients). In addition, percentage distribution of Rh system was also calculated, in which Rh+ve Group was high and more common in DM patients as compared to pre-diabetics; numerically given as: Rh+ve Group (80% in DM vs. 72% in pre-diabetics). Different views and dimensions of the research topic were studied through literature support, some have found no any association and some established a positive association still some were not clear in making a solid conclusion. It is concluded that DM has a positive correlation with ABO blood groups, and people with Group-B have increased susceptibility to DM disease.
本研究的主要目的是在巴基斯坦卡拉奇的八个不同城镇的当地人群中，找出 ABO 血型或 Rh 与糖尿病（DM）之间可能存在的关联。为此，在 2019 年 6 月至 2020 年 2 月的 9 个月期间，在卡拉奇进行了一项调查，以便对这些城镇进行实际观察。在卡拉奇的十八个城镇中，仅从八个城镇收集了样本（N=584），并给每个城镇分配了一个代码号。糖尿病组样本为（n1=432），前驱糖尿病组样本为（n2=152）。使用 Abbott 公司的血糖仪对随机血糖（RBS）和空腹血糖（FBS）进行检测，使用标准抗血清检测 ABO/Rh 血型。通过向所有登记的受试者征求知情同意，以伦理的方式进行健康评估技术。最后，使用 SPSS 版本 20 对数据进行分析。在我们目前的研究中，对糖尿病和前驱糖尿病个体之间的 ABO 血型频率进行了比较。血型-B 的百分比值为：（DM 中为 32%，前驱糖尿病中为 31%），其次是血型-O：（DM 中为 18%，前驱糖尿病中为 11%）。与“B”和“O”组相反，A 组和 AB 组在前驱糖尿病患者中的分布百分比高于糖尿病患者，具体为：A 组（前驱糖尿病患者中为 32%，糖尿病患者中为 26%）和 AB 组（前驱糖尿病患者中为 26%，糖尿病患者中为 24%）。此外，还计算了 Rh 系统的百分比分布，其中 Rh+ve 组在糖尿病患者中更为常见，与前驱糖尿病患者相比，其数值为：Rh+ve 组（DM 中为 80%，前驱糖尿病中为 72%）。通过文献支持研究了该研究主题的不同观点和维度，有些没有发现任何关联，有些建立了积极的关联，有些则不清楚如何得出确凿的结论。结论是，DM 与 ABO 血型有正相关关系，B 型血的人患 DM 病的易感性增加。
