Khattak Imranud Din, Khan Taj Muhammad, Khan Purdil, Shah Syed Mukhtar Ali, Khattak Sania Tanveer, Ali Anwar
Department of Pathology, Saidu Teaching Hospital/Saidu Medical College, Swat, Pakistan.
J Ayub Med Coll Abbottabad. 2008 Oct-Dec;20(4):127-9.
Up till now about 400 red cells antigen have been identified. The majority are inherited by Mendelian Fashion. The ABO blood group system was first to be identified and RH blood group system was the 4th one, both are most important for blood transfusion purposes. This study is conducted to determine the frequency of ABO and Rhesus (Rh) blood groups in District Swat, NWFP, Pakistan. It is a cross sectional prospective study and was conducted at Saidu Teaching Hospital district Swat, over a period of one year. (1st Jan. 2007 to 31st Dec, 2007).
A total of 22897 subjects were included in this study. Patients were collected from different wards of Saidu Teaching Hospital while the donors from common population. From each subject blood was collected, ABO and Rh blood grouping were carried out by tile method using commercially prepared anti sera. The frequency of each type was calculated.
Out of 22897 subjects 17141 (74.86%) were male subjects and 5756 (25.140%) were female. Out of 17141 male subjects 15597 (90.99%) and out of 5756 female subjects 5040 (87.56%) were found to be Rh-positive. The frequency of Rh-negative group in male subjects were (9.01%) where as in female subjects were (12.22%). The frequency of A, B, O and AB groups in Rh-positive male subjects were 25.63%, 29.54%, 26.04% and 9.78%, amongst female subjects, it was 24.53%, 28.06%, 25.54% and 9.43% respectively. In Rh-negative male subjects the frequency of A, B, O and AB is 2.25%, 2.88%, 3.01% and 0.88%, while amongst females it is 3.54%, 4.24%, 3.74% and 0.92% respectively.
It is concluded from this study that frequency of Rh-positive blood group is B, O, A, and AB in both gender. Where as the most common Rh-negative in male and female subjects are O, B, A, AB, and B, O, A, and AB respectively.
截至目前,已确定约400种红细胞抗原。大多数抗原按孟德尔方式遗传。ABO血型系统是最早被发现的,Rh血型系统是第4个被发现的,这两个血型系统对于输血目的而言最为重要。本研究旨在确定巴基斯坦西北边境省斯瓦特地区ABO和恒河猴(Rh)血型的频率。这是一项横断面前瞻性研究,在斯瓦特地区的赛杜教学医院进行,为期一年(2007年1月1日至2007年12月31日)。
本研究共纳入22897名受试者。患者来自赛杜教学医院的不同病房,而献血者来自普通人群。从每位受试者采集血液,使用商业制备的抗血清通过玻片法进行ABO和Rh血型鉴定。计算每种血型的频率。
在22897名受试者中,17141名(74.86%)为男性,5756名(25.14%)为女性。在17141名男性受试者中,15597名(90.99%)为Rh阳性,在5756名女性受试者中,5040名(87.56%)为Rh阳性。男性受试者中Rh阴性组的频率为(9.01%),而女性受试者中为(12.22%)。Rh阳性男性受试者中A、B、O和AB血型的频率分别为25.63%、29.54%、26.04%和9.78%,女性受试者中分别为24.53%、28.06%、25.54%和9.43%。Rh阴性男性受试者中A、B、O和AB血型的频率分别为2.25%、2.88%、3.01%和0.88%,而女性受试者中分别为3.54%、4.24%、3.74%和0.92%。
本研究得出结论,Rh阳性血型在两性中的频率依次为B、O、A和AB。而男性和女性受试者中最常见的Rh阴性血型分别为O、B、A、AB和B、O、A、AB。