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[骨水泥植入期间循环与呼吸反应的发病机制研究。动物实验(作者译)]

[Investigations of pathogenesis of reactions in circulation and respiration during the implantation of bone cements. animal experiments (author's transl)].

作者信息

Rudigier J, Grünert A

出版信息

Arch Orthop Trauma Surg (1978). 1978 Apr 18;91(2):85-95. doi: 10.1007/BF00378889.

DOI:10.1007/BF00378889
PMID:350191
Abstract

This paper shows the effects of the increase in pressure in the medullary cavity in the blood circulation and the respiration observed during implantation of bone cement with animal experiments. The pathomechanism is also examined. The reactions of the respiration and the circulation, when observed, resulted in the intramedullary increase in pressure. These are nerval reflexes caused by the innervation in the medullary cavity and are not reactions of the monomer, which may come into the circulation during the polimerization of bone cement. These reactions are very different from those caused by the fatal obstruction of the pulmonary blood vessels through bone marrow ingredients. This is the effect of an insufficient prevention of increase in medullary pressure during cement implantation.

摘要

本文通过动物实验展示了在骨水泥植入过程中,髓腔内压力升高对血液循环和呼吸的影响。同时也研究了其病理机制。观察到呼吸和循环反应导致了髓腔内压力升高。这些是由髓腔内神经支配引起的神经反射,而非骨水泥聚合过程中可能进入循环的单体的反应。这些反应与因骨髓成分导致肺血管致命性阻塞所引起的反应截然不同。这是在骨水泥植入过程中对髓腔压力升高预防不足的结果。

相似文献

1
[Investigations of pathogenesis of reactions in circulation and respiration during the implantation of bone cements. animal experiments (author's transl)].[骨水泥植入期间循环与呼吸反应的发病机制研究。动物实验(作者译)]
Arch Orthop Trauma Surg (1978). 1978 Apr 18;91(2):85-95. doi: 10.1007/BF00378889.
2
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引用本文的文献

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The Bone Cement Hypercoagulation Syndrome: Pathophysiology, Mortality, and Prevention.骨水泥高凝综合征:病理生理学、死亡率和预防。
Clin Appl Thromb Hemost. 2023 Jan-Dec;29:10760296231198036. doi: 10.1177/10760296231198036.
2
New clinico-pathophysiological studies on the bone cement implantation syndrome.骨水泥植入综合征的新临床病理生理学研究
Arch Orthop Trauma Surg (1978). 1980;97(4):263-74. doi: 10.1007/BF00380707.
3
Intraoperative transesophageal two-dimensional echocardiography in total hip replacement.全髋关节置换术中的术中经食管二维超声心动图

本文引用的文献

1
Blood pressure and bone cement.血压与骨水泥
Br Med J. 1971 May 15;2(5758):404. doi: 10.1136/bmj.2.5758.404-b.
2
Cardiac arrest associated with bone cement.与骨水泥相关的心搏骤停。
Br Med J. 1970 Aug 8;3(5718):326. doi: 10.1136/bmj.3.5718.326.
3
[Vital intrasurgical complications due to fat embolism after the installation of total endoprostheses with polymethylmethacrylate].[安装含聚甲基丙烯酸甲酯的全关节假体后因脂肪栓塞导致的术中重要并发症]
Arch Orthop Trauma Surg (1978). 1986;105(5):274-8. doi: 10.1007/BF00449925.
4
Pharmacokinetics of methylmethacrylate monomer during total hip replacement in man.人工全髋关节置换术中甲基丙烯酸甲酯单体的药代动力学
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4
Fat embolism and cerebral infarction after use of methylmethacrylic cement.使用甲基丙烯酸甲酯骨水泥后发生脂肪栓塞和脑梗死。
Br Med J. 1972 Sep 23;3(5829):740-1. doi: 10.1136/bmj.3.5829.740.
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[Prevention of fat embolism complicating hip joint prosthesis using choline phospholipids and decompression. Animal experiment].
Arch Orthop Unfallchir. 1972;72(3):272-6. doi: 10.1007/BF00416418.
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[Fat embolism following the use of bone cement in hip joint prosthesis. Animal experiments].
Arch Orthop Unfallchir. 1972;72(2):114-21. doi: 10.1007/BF00416526.
7
[Penetration of methylmethacrylate-monomer in blood circulation following hip joint prosthesis surgery in man].[人工髋关节置换术后甲基丙烯酸甲酯单体在人体血液循环中的渗透情况]
Chirurg. 1974 May;45(5):236-42.
8
Elevation of intramedullary pressure when methylmethacrylate is inserted in total hip arthroplasty.全髋关节置换术中插入甲基丙烯酸甲酯时髓内压力的升高。
J Bone Joint Surg Am. 1974 Jun;56(4):714-8.
9
The intramedullary pressure during the bone marrow trauma of total hip replacement surgery.
Ups J Med Sci. 1974;79(1):51-4. doi: 10.3109/03009737409178390.
10
Blood clearance and acute pulmonary toxicity of methylmethacrylate in dogs after simulated arthroplasty and intravenous injection.模拟关节置换术后静脉注射甲基丙烯酸甲酯对犬的血液清除率及急性肺毒性
J Bone Joint Surg Am. 1973 Dec;55(8):1621-8.