丙烯酸骨水泥对兔和猫的心血管影响。

Pelling D, Butterworth K R

Br Med J. 1973 Jun 16;2(5867):638-41. doi: 10.1136/bmj.2.5867.638.

The cardiovascular responses to forcing acrylic bone cement, Plasticine, or soft paraffin wax into the medullary cavity of the femur have been studied in rabbits and cats. An acute fall in blood pressure, occurring within a few seconds of insertion, was demonstrated with each substance. In a few of the animals the blood pressure response had a second more protracted component and it is suggested that more than one mechanism is involved. The cardiovascular effects that have been observed in man when acrylic cement is used in prosthetic hip surgery also may be due to more than one mechanism.

在兔子和猫身上研究了将丙烯酸骨水泥、橡皮泥或软石蜡注入股骨髓腔时的心血管反应。每种物质在注入后几秒钟内都会导致血压急剧下降。少数动物的血压反应有第二个持续时间更长的成分，提示涉及多种机制。在人工髋关节置换手术中使用丙烯酸骨水泥时，在人体观察到的心血管效应也可能是由多种机制引起的。