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印度南部泰米尔纳德邦城市和郊区学童近视患病率:来自 Sankara Nethralaya 泰米尔纳德邦依视路近视(STEM)研究的结果。

Prevalence of myopia among urban and suburban school children in Tamil Nadu, South India: findings from the Sankara Nethralaya Tamil Nadu Essilor Myopia (STEM) Study.

机构信息

Myopia Clinic, Sankara Nethralaya, Unit of Medical Research Foundation, Chennai, India.

School of Medicine, Faculty of Health, Deakin University, Geelong, Victoria, Australia.

出版信息

Ophthalmic Physiol Opt. 2022 Mar;42(2):345-357. doi: 10.1111/opo.12943. Epub 2022 Jan 12.

Abstract

PURPOSE

To report the baseline prevalence of myopia among school children in Tamil Nadu, South India from a prospective cohort study.

METHODS

Children between the ages of 5 and 16 years from 11 schools in two districts of Tamil Nadu underwent vision screening. All children underwent visual acuity assessment using a Pocket Vision Screener followed by non-cycloplegic open-field autorefraction (Grand Seiko WAM-5500). Myopia was defined as a spherical equivalent (SE) refraction of ≤-0.75 D and high myopia was defined as SE ≤ -6.00 D. Distribution of refraction, biometry and factors associated with prevalence of myopia were the outcome measures.

RESULTS

A total of 14,699 children completed vision screening, with 2% (357) of them having ocular abnormalities other than refractive errors or poor vision despite spectacle correction. The remaining 14,342 children (7557 boys; 52.69%) had a mean age of 10.2 (Standard Deviation [SD] 2.8) years. A total of 2502 had myopia in at least one eye, a prevalence of 17.5% (95% CI: 14.7-20.5%), and 74 (0.5%; 95% CI: 0.3-0.9%) had high myopia. Myopia prevalence increased with age (p < 0.001), but sex was not associated with myopia prevalence (p = 0.24). Mean axial length (AL; 23.08 (SD = 0.91) mm) and mean anterior chamber depth (ACD; 3.45 (SD = 0.27) mm) positively correlated with age (p < 0.001). The mean flat (K1; 43.37 (SD = 1.49) D) and steep (K2; 44.50 (SD = 1.58) D) corneal curvatures showed negative correlation with age (p = 0.02 and p < 0.001, respectively). In the multivariable logistic regression, older age and urban school location had higher odds for prevalence of myopia.

CONCLUSION

The baseline prevalence of myopia among 5- to 16-year-old children in South India is larger than that found in previous studies, indicating that myopia is becoming a major public health problem in this country.

摘要

目的

报告来自印度南部泰米尔纳德邦一项前瞻性队列研究中,学童近视的基线患病率。

方法

来自泰米尔纳德邦两个区 11 所学校的 5 至 16 岁儿童进行了视力筛查。所有儿童均使用 Pocket Vision Screener 进行视力评估,然后进行非睫状肌散瞳开放式自动验光(Grand Seiko WAM-5500)。近视定义为等效球镜(SE)屈光度≤-0.75D,高度近视定义为 SE ≤-6.00D。折射分布、生物测量和与近视患病率相关的因素是本研究的结局指标。

结果

共有 14699 名儿童完成了视力筛查,其中 2%(357 名)的儿童除屈光不正或视力差外,还有其他眼部异常,尽管经过眼镜矫正。其余 14342 名儿童(7557 名男孩;52.69%)的平均年龄为 10.2(标准差[SD] 2.8)岁。共有 2502 名儿童至少一只眼近视,患病率为 17.5%(95%可信区间:14.7-20.5%),74 名(0.5%;95%可信区间:0.3-0.9%)患有高度近视。近视患病率随年龄增长而增加(p<0.001),但性别与近视患病率无关(p=0.24)。平均眼轴(AL;23.08(SD=0.91)mm)和平均前房深度(ACD;3.45(SD=0.27)mm)与年龄呈正相关(p<0.001)。平均平坦角膜曲率(K1;43.37(SD=1.49)D)和陡峭角膜曲率(K2;44.50(SD=1.58)D)与年龄呈负相关(p=0.02 和 p<0.001)。在多变量逻辑回归中,年龄较大和城市学校地点的近视患病率更高。

结论

印度南部 5 至 16 岁儿童近视的基线患病率大于以往研究发现的患病率,表明近视正在成为该国一个主要的公共卫生问题。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/05a9/9304285/18ccce8f79df/OPO-42-345-g001.jpg

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