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基于铜硫属化合物的多模态纳米诊疗剂

Copper-Chalcogenide-Based Multimodal Nanotheranostics.

作者信息

Zhang Hao, Zeng Xiaoqing, Li Zhen

机构信息

College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, P. R. China.

Center for Molecular Imaging and Nuclear Medicine, State Key Laboratory of Radiation Medicine and Protection, School for Radiological and Interdisciplinary Sciences (RAD-X), Soochow University, Collaborative Innovation Center of Radiation Medicine of Jiangsu Higher Education Institutions, Suzhou 215123, P. R. China.

出版信息

ACS Appl Bio Mater. 2020 Oct 19;3(10):6529-6537. doi: 10.1021/acsabm.0c00937. Epub 2020 Sep 25.

DOI:10.1021/acsabm.0c00937
PMID:35019384
Abstract

Nanostructured copper chalcogenides have a wealth of intrinsic unique properties and hold great potential in the fields of energy conversion and theranostics. This Spotlight summarizes the latest bioapplications of an important type of copper chalcogenides, , CuSe nanoparticles, which have been successfully investigated for molecular imaging (, photoacoustic imaging, X-ray computed tomography, magnetic resonance imaging, and single photon emission computed tomography), and therapy of tumors including photothermal therapy, chemodynamic therapy, photodynamic therapy, and immunotherapy. The broad bioapplications of CuSe nanoparticles highlight their great promise in maintaining good health.

摘要

纳米结构的铜硫属化合物具有大量内在的独特性质,在能量转换和诊疗领域具有巨大潜力。本专题综述了一种重要的铜硫属化合物——硒化铜(CuSe)纳米颗粒的最新生物应用,该纳米颗粒已成功用于分子成像(如光声成像、X射线计算机断层扫描、磁共振成像和单光子发射计算机断层扫描)以及肿瘤治疗,包括光热疗法、化学动力疗法、光动力疗法和免疫疗法。CuSe纳米颗粒广泛的生物应用凸显了它们在维护健康方面的巨大前景。

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