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[孕酮对未成年雌性大鼠腺垂体影响的形态学研究]

[Morphological studies of the effects of progesterone on the adenohypophysis of the impuberal female rat].

作者信息

Scandroglio R, Baratta L, Baratta B

出版信息

Ateneo Parmense Acta Biomed. 1977;48(5):443-81.

PMID:350233
Abstract

At optical microscope and at electronic microscope it has been examined the adenohypophysis of Wistar albino impuberal female rats after administration of progesterone. It has come out that the progesterone influences in different ways the activity of pituitary gonadotropic cells (FSH and LH cells) according to the quantity and according to the way it affects either rapidly or within an extended period, on intact or on spayed animals, in the morning or in the afternoon. For what concerns the influence of the hormone, it has also come out to be variable as it may concern, according to the cases, a single or both cellular types, and it can appear with symptoms of secretion, with symptoms of excretion or with both symptoms. According to the verified data, the possible ways of action of progesterone on the hypothalamo-hypophyseal unit are discussed.

摘要

在光学显微镜和电子显微镜下,对给予孕酮后的未成熟Wistar白化雌性大鼠的腺垂体进行了检查。结果表明,孕酮根据其剂量、作用方式(快速或长期)、作用对象(完整动物或去卵巢动物)以及给药时间(上午或下午),以不同方式影响垂体促性腺细胞(FSH和LH细胞)的活性。关于该激素的影响,还发现其作用可能因情况而异,可能涉及单一或两种细胞类型,并且可能表现为分泌症状、排泄症状或两种症状都有。根据已证实的数据,讨论了孕酮对下丘脑 - 垂体单位的可能作用方式。

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