Department of Laboratory Medicine, Changzheng Hospital, Naval Medical University, Shanghai 20003, P.R. China.
Department of Rheumatology and Immunology, Changzheng Hospital, Naval Medical University, Shanghai 20003, P.R. China.
J Int Med Res. 2022 Jan;50(1):3000605211072783. doi: 10.1177/03000605211072783.
We report the first case of a woman with Behcet's disease (BD) with multiple hand ulcers secondary to coninfection by and resulting in necrotizing fasciitis. She had a long history of BD including long courses of prednisone and immunosuppressants. The patient was hospitalized for multiple superficial ulcers, swelling, and infection of the hands. After admission, pus culture examination revealed rare coinfection by and . We administered moxifloxacin and vancomycin to control infection and methylprednisolone to control BD. We performed incision, drainage, and debridement of the ulcer surface on the hands to reduce the pus on the wound surface. infections occur in immunosuppressed patients and contribute to coinfections, particularly in patients with BD in whom destruction of the skin immune barrier increases risk to secondary infections. For severe and complicated hand infections, efforts should be made to identify pathogenic microorganisms so appropriate antibiotics and other interventions can be given to control the infection.
我们报告了首例贝赫切特病（BD）女性患者，其手部多处溃疡继发 和 合并感染导致坏死性筋膜炎。该患者 BD 病史较长，曾长期使用泼尼松龙和免疫抑制剂。患者因手部多处浅溃疡、肿胀和感染入院。入院后，脓液培养检查发现 和 罕见合并感染。我们给予莫西沙星和万古霉素控制感染，并用甲泼尼龙控制 BD。我们对手部溃疡表面进行切开、引流和清创，以减少伤口表面的脓液。 感染发生于免疫抑制患者，可导致合并感染，特别是在皮肤免疫屏障破坏增加继发感染风险的 BD 患者中。对于严重和复杂的手部感染，应努力确定致病微生物，以便给予适当的抗生素和其他干预措施来控制感染。
