人类感染侵蚀艾肯菌：6 例报告及文献复习。
Eikenella corrodens infections in human: Reports of six cases and review of literatures.
机构信息
Department of Medical Laboratory, Li Huili Hospital Affiliated to Ningbo University, Ningbo, China.
Department of Medical Laboratory, Ningbo First Hospital, Ningbo, China.
出版信息
J Clin Lab Anal. 2022 Feb;36(2):e24230. doi: 10.1002/jcla.24230. Epub 2022 Jan 12.
PURPOSE
To investigate clinical characteristics of six cases of Eikenella corrodens infection in Ningbo First Hospital in China in recent 2 years.
METHODS
We retrospectively analyze medical records of six cases of E. corrodens infection in Ningbo First Hospital from 2020 to 2021. And we describe the gender, age, clinical manifestations, antimicrobial administration, and treatment of the six patients.
RESULTS
Five of the patients had deep infection and they were treated with surgical drainage or abscess resection plus antimicrobial administration. After treatment, five patients were discharged and recovered well, and another patient was transferred to another hospital for further treatment. All the six cases were in line with the reports on the clinical characteristics of patients infected with E. corrodens at home and abroad before 2021.
CONCLUSION
Eikenella corrodens is a part of the normal flora of human oropharynx, but it can migrate to other parts of the human body to cause severe invasive disease in humans. Although it is susceptible to most antimicrobials, it needs debridement in the treatment of deep infection.
目的
研究中国宁波第一医院近 2 年来 6 例侵蚀艾肯菌感染的临床特征。
方法
回顾性分析 2020 年至 2021 年宁波第一医院 6 例侵蚀艾肯菌感染患者的病历资料。描述 6 例患者的性别、年龄、临床表现、抗菌药物使用及治疗情况。
结果
5 例患者为深部感染，行手术引流或脓肿切除加抗菌药物治疗。治疗后，5 例患者出院，恢复良好，另 1 例患者转往其他医院进一步治疗。6 例患者均符合 2021 年前国内外关于侵蚀艾肯菌感染患者临床特征的报道。
结论
侵蚀艾肯菌是人类口咽部正常菌群的一部分，但可迁移至人体其他部位引起严重侵袭性疾病。虽然它对大多数抗菌药物敏感，但在深部感染的治疗中需要清创。
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