Chen Xin, Lin Guang-Xun, Rui Gang, Chen Chien-Min, Kotheeranurak Vit, Wu Hua-Jian, Zhang Huang-Lin
Department of Fifth Surgical, Foresea Life Insurance Guangzhou General Hospital, Guangzhou, People's Republic of China.
Department of Orthopedics, The First Affiliated Hospital of Xiamen University, School of Medicine, Xiamen University, Xiamen, People's Republic of China.
J Pain Res. 2022 Jan 6;15:41-52. doi: 10.2147/JPR.S329162. eCollection 2022.
Previous studies have demonstrated that minimally invasive (MI) transforaminal lumbar interbody fusion (TLIF) is comparable to the open approach in terms of efficacy and safety. However, few comparative studies of surgical procedures in patients with obesity show that they may react differently to open-TLIF (O-TLIF) and MI-LTIF approaches.
The main indicators were complications, visual analog scale (VAS) score, and Oswestry Disability Index (ODI) score, and secondary indicators were operative time, blood loss, and hospital stay.
No significant differences in the VAS and ODI scores for back pain at the last follow-up and wound infection rates were observed between the two groups. Dural tear incidence and complication rate were significantly lower in the MI-TLIF group than that in the O-TLIF group (P = 0.002 and 0.001, respectively). No significant difference in operative time was found between the two groups. There was less blood loss and shorter hospital stay (P = 0.001 and 0.002, respectively) in the MI-TLIF group than that in the O-TLIF group.
Compared with O-TLIF, MI-TLIF is an effective and safe surgical option for patients with obesity, which resulted in similar improvements in pain and functional disability, as well as a lower complication rate.
既往研究表明,微创经椎间孔腰椎椎体间融合术(MI-TLIF)在疗效和安全性方面与开放手术相当。然而,很少有针对肥胖患者手术方式的比较研究表明,他们对开放经椎间孔腰椎椎体间融合术(O-TLIF)和MI-TLIF手术方式的反应可能不同。
主要指标为并发症、视觉模拟评分(VAS)和奥斯维斯特里功能障碍指数(ODI)评分,次要指标为手术时间、失血量和住院时间。
两组在末次随访时的背痛VAS和ODI评分以及伤口感染率方面无显著差异。MI-TLIF组的硬脊膜撕裂发生率和并发症发生率显著低于O-TLIF组(分别为P = 0.002和0.001)。两组手术时间无显著差异。MI-TLIF组的失血量更少,住院时间更短(分别为P = 0.001和0.002)。
与O-TLIF相比,MI-TLIF对肥胖患者是一种有效且安全的手术选择,在疼痛和功能障碍改善方面相似,且并发症发生率更低。