Department of Physical and Rehabilitation Medicine, Iuliu Haţieganu University of Medicine and Pharmacy, Cluj-Napoca, Romania;
Rom J Morphol Embryol. 2021 Apr-Jun;62(2):599-603. doi: 10.47162/RJME.62.2.29.
Gout is one of the most common types of inflammatory arthritis. Four stages have been described in its evolution: asymptomatic hyperuricemia, acute gouty arthritis, intercritical gout and chronic tophaceous gout. Monosodium urate crystals deposits are more frequently encountered in hyaline cartilage, tendon sheaths, articular bursae, bone epiphysis, synovium, and skin. Pathological fractures that occur at the formation sites of gout tophi have been rarely described in gout. Bimalleolar fractures often occur following a trauma. We present the case of a 56-year-old patient, diagnosed with chronic gout for over 12 years, with tophi in the upper and lower limbs, who presented accusing mechanical pain in the left tibio-tarsal joint and impaired function of the hands. The clinical examination showed bilateral multiple destructive gout tophi in the hands, forearms, elbows, feet, ankles, and lower legs, while the left ankle exhibited an important varus deformity. Computed tomography examination of the left ankle showed multiple gout tophi with bone erosions and a bimalleolar pathological fracture. The patient underwent pharmacological treatment, physical therapy and the ankle was immobilized in a knee-ankle-foot orthosis, with subsequent orthopedic surgical treatment for fracture fixation, to improve functional status. We have chosen to present this case given the multiple disabilities of the patient, which have improved following the rehabilitation treatment.
痛风是最常见的炎症性关节炎类型之一。其发展过程中描述了四个阶段:无症状高尿酸血症、急性痛风性关节炎、间歇期痛风和慢性痛风石性痛风。尿酸单钠晶体沉积更常见于透明软骨、腱鞘、关节囊、骨骨骺、滑膜和皮肤。痛风石形成部位的病理性骨折在痛风中很少见。双踝骨折常因外伤引起。我们介绍了一位 56 岁的患者,他被诊断为慢性痛风已有 12 年以上,上肢和下肢有痛风石,左踝跖关节出现机械性疼痛,并伴有手部功能障碍。临床检查显示双手、前臂、肘部、脚、踝关节和小腿双侧多处破坏性痛风石,左踝关节有明显的内翻畸形。左踝关节 CT 检查显示多发性痛风石伴骨侵蚀和双踝病理性骨折。患者接受了药物治疗、物理治疗和踝部膝关节-踝关节-足部矫形器固定,随后进行矫形外科手术固定骨折,以改善功能状态。我们选择介绍这个病例,是因为患者有多种残疾,经过康复治疗后有所改善。