Sugita M, Aikawa H, Yamasaki T, Suzuki K, Minowa H, Etoh R, Kasuga H
Department of Public Health, School of Medicine, Tokai University, Kanagawa, Japan.
Tokai J Exp Clin Med. 1987 Nov;12(4):215-22.
The biological monitoring for exposure to toluene is based on the measurement of urinary hippuric acid concentration (HA-U). In occupational health, workers exposed to toluene are examined for HA-U, because collection of urine samples is easy. The HA-U data of an engineer who did not use toluene occupationally showed relatively high values. It was indicated that he went to ski every weekend in winter and had used spray ski-wax and remover which contained toluene. The ski-club members of Tokai University, School of Medicine who used such sprays were examined for HA-U at the ski training camp. It was revealed that the use of these sprays elevated the HA-U values remarkably. Therefore, the use of sprays, especially in the winter season, can be one of confounding factors for biological monitoring of occupational exposure to toluene based on measurement of HA-U.