Division of Infectious Diseases, National Medical Center, Seoul, Korea.
Department of Internal Medicine, National Medical Center, Seoul, Korea.
J Korean Med Sci. 2022 Jan 17;37(3):e31. doi: 10.3346/jkms.2022.37.e31.
Since severe acute respiratory syndrome-coronavirus-2 variant B.1.1.529 (omicron) was first reported to the World Health Organization on November 24, 2021, the cases of the omicron variant have been detected in more than 90 countries over the last month. We investigated the clinical and epidemiological characteristics of the first 40 patients with the omicron variant who had been isolated at the National Medical Center in South Korea during December 4-17, 2021. The median age of the patients was 39.5 years. Twenty-two patients (55%) were women. Seventeen patients (42.5%) were fully vaccinated, and none were reinfected with the omicron. Eighteen (45%) had recent international travel history. Half of the patients (19, 47.5%) were asymptomatic, while the others had mild symptoms. Six patients (15%) showed lung infiltrations on chest image; however, none required supplemental oxygen. These mild clinical features are consistent with recent case reports on the omicron variant from other countries.
自 2021 年 11 月 24 日首次向世界卫生组织报告严重急性呼吸综合征冠状病毒 2 变异株 B.1.1.529（奥密克戎）以来，在过去一个月中，已在 90 多个国家发现了奥密克戎变异株的病例。我们调查了 2021 年 12 月 4 日至 17 日在韩国国家医疗中心隔离的 40 名奥密克戎变异株患者的临床和流行病学特征。患者的中位年龄为 39.5 岁。22 名患者（55%）为女性。17 名患者（42.5%）已完全接种疫苗，且无人再次感染奥密克戎。18 名患者（45%）有近期国际旅行史。一半的患者（19 名，47.5%）无症状，而其余患者症状较轻。6 名患者（15%）胸部影像显示肺部浸润；但无人需要补充氧气。这些较轻的临床特征与其他国家最近关于奥密克戎变异株的病例报告一致。
