Yamane Masahiro, Kobayashi Hirotoshi, Hattori Yutaka, Koizumi Ayaka, Mori Shohei, Igarashi Yuichi, Shigehara Fumi, Takashima Jumpei, Yamazaki Kenji, Sugimoto Hitoshi, Miura Fumihiko, Taniguchi Keizo, Matsutani Noriyuki
Dept. of Surgery, Teikyo University Hospital, Mizonokuchi.
Gan To Kagaku Ryoho. 2021 Dec;48(13):1963-1965.
A 47-year-old woman with a complaint of weight loss for the past 5 months was referred to our hospital. Colonoscopy revealed advanced rectal cancer 20 cm from the anal verge. The patient had left hydronephrosis caused by ureteral invasion. Firstly, we performed transverse colostomy and left nephrostomy. After 8 courses of capecitabine, oxaliplatin plus bevacizumab( CAPOX plus Bmab)therapy, colonoscopy and computed tomography revealed shrinkage of both the primary and metastatic lesions. Laparoscopic high anterior resection was performed, and the left ureter was successfully preserved. The patient received chemotherapy after surgery. Neither local recurrence nor enlargement of metastases has been observed 8 months after surgery.
一名47岁女性因过去5个月体重减轻前来我院就诊。结肠镜检查发现距肛门边缘20 cm处有进展期直肠癌。患者因输尿管侵犯导致左肾积水。首先,我们进行了横结肠造口术和左肾造瘘术。在接受8个疗程的卡培他滨、奥沙利铂联合贝伐单抗(CAPOX加Bmab)治疗后,结肠镜检查和计算机断层扫描显示原发灶和转移灶均缩小。遂行腹腔镜高位前切除术,成功保留了左输尿管。患者术后接受了化疗。术后8个月未观察到局部复发和转移灶增大。