Department of Acupuncture and Tuina, Changchun University of Chinese Medicine, Changchun, China.
Department of Acupuncture and Tuina, The Affiliated Hospital of Changchun University of Chinese Medicine, Changchun, China.
Medicine (Baltimore). 2021 Dec 3;100(48):e28042. doi: 10.1097/MD.0000000000028042.
Diabetic peripheral neuropathy (DPN) is one of the most common microvascular complications of diabetes mellitus, with an incidence ranging from 60% to 90%. With the change in modern dietary structure, the incidence of diabetes is increasing year by year, and DPN is also on the rise. Acupuncture and Tuina treatments are often combined to treat DPN; however, there has been no meta-analysis on their synergistic effect; therefore, we aimed to perform a systematic review and meta-analysis to estimate the effectiveness of acupuncture combined with Tuina in DPN treatment.
Nine electronic databases were retrieved for this study. The English databases mainly retrieved PubMed, Web of Science, Embase, AMED, and the Cochrane Library, while the CNKI, VIP, CBM, and Wanfang databases were used to retrieve the Chinese literature; there was no definite time limit for the retrieval literature, and the languages were limited to Chinese and English. We will consider articles published between database initiation and November 2021. We used Review Manager 5.4 software provided by the Cochrane Collaborative Network for statistical analysis. We then assessed the quality and risk of the included studies and observed the outcome measures.
This study provides a high-quality synthesis to assess the effectiveness and safety of acupuncture combined with Tuina for treating DPN.
This systematic review provided evidence to determine whether acupuncture combined with Tuina is an effective and safe intervention for patients with DPN.
The protocol for this systematic review does not require ethical approval because it does not involve humans. This article will be published in peer-reviewed journals and presented at relevant conferences.
INPLASY2021110017.
糖尿病周围神经病变（DPN）是糖尿病最常见的微血管并发症之一，发病率为 60%~90%。随着现代饮食结构的改变，糖尿病的发病率逐年上升，DPN 也呈上升趋势。针灸和推拿治疗常联合用于 DPN 的治疗，但两者联合的协同作用尚未进行荟萃分析，因此，我们旨在进行系统评价和荟萃分析，以评估针灸联合推拿治疗 DPN 的疗效。
本研究共检索了 9 个电子数据库。英文数据库主要检索了 PubMed、Web of Science、Embase、AMED 和 Cochrane 图书馆，而中文文献则检索了中国知网、维普、中国生物医学文献数据库和万方数据库；检索文献没有明确的时间限制，语言仅限于中文和英文。我们将考虑从数据库建立到 2021 年 11 月之间发表的文章。我们使用 Cochrane 协作网提供的 Review Manager 5.4 软件进行统计分析。然后，我们评估了纳入研究的质量和风险，并观察了结局指标。
本研究提供了高质量的综合评估，以评估针灸联合推拿治疗 DPN 的疗效和安全性。
本系统评价提供了证据，以确定针灸联合推拿是否是 DPN 患者的一种有效且安全的干预措施。
本系统评价的方案不需要伦理批准，因为它不涉及人类。本文将发表在同行评议的期刊上，并在相关会议上展示。
INPLASY2021110017。
