Tinoco Fernanda Viola, Morelli Simone, de Farias Brito Marilene, Oliveira Pereira Gabriela, Correia Oliveira Mariana, Diakou Anastasia, Colombo Mariasole, Frangipane di Regalbono Antonio, Traversa Donato
Clinica Veterinária Cães & Gatos, Barra do Piraí 27113-150, Brazil.
Faculty of Veterinary Medicine, University of Teramo, 64100 Teramo, Italy.
Animals (Basel). 2022 Jan 6;12(2):128. doi: 10.3390/ani12020128.
The lungworm is one of the main causes of respiratory diseases in cats worldwide. This report describes the unusual case of a kitten infected with and presented to a veterinary clinic in Brazil with lethargy, dysphagia, non-ambulatory tetraplegia, and pelvic limbs bilateral myoclonus. The clinical picture of the kitten worsened with generalized flaccid tetraplegia and death a few days after hospitalization. At necropsy, hemorrhagic necrosis and subarachnoid hemorrhages were detected in several areas of the central nervous system. Nematode stages were found at post-mortem histological examinations in lungs, cerebellum, subarachnoid space of the brain and spinal cord. Microscopic and molecular (PCRs-coupled-sequencing protocols) examination showed the presence of in histological samples. This study describes the first neurological aelurostrongylosis due to ectopic localization of adult worms in the central nervous system of a cat, causing acute hemorrhagic multifocal meningoencephalomyelitis. Further studies are necessary to elucidate whether unusual localizations and the migration of are more frequent than expected.
肺线虫是全球范围内猫呼吸系统疾病的主要病因之一。本报告描述了一只小猫感染肺线虫的罕见病例，该小猫被送往巴西一家兽医诊所，出现嗜睡、吞咽困难、非行走性四肢瘫痪以及双侧后肢肌阵挛症状。小猫的临床症状恶化，出现全身性弛缓性四肢瘫痪，并在住院几天后死亡。尸检时，在中枢神经系统的几个区域检测到出血性坏死和蛛网膜下腔出血。在死后组织学检查中，在肺、小脑、脑蛛网膜下腔和脊髓中发现了线虫阶段。显微镜和分子（聚合酶链反应-测序方案）检查显示组织学样本中存在肺线虫。本研究描述了首例因成虫异位寄生于猫中枢神经系统导致急性出血性多灶性脑膜脑脊髓炎的神经性猫圆线虫病。需要进一步研究以阐明肺线虫异常定位和迁移是否比预期更频繁。
