大于胎龄儿：糖尿病母亲婴儿面临的困境。

Large for gestational age: dilemma of the infant of the diabetic mother.

作者信息

Goldkrand J W, Lin J Y

机构信息

Division of Maternal-Fetal Medicine, Albany Medical Center Hospital, New York 12208.

出版信息

J Perinatol. 1987 Fall;7(4):282-7.

PMID:3505263

Abstract

A retrospective analysis was undertaken of 128 pregnancies (131 infants) complicated by diabetes; 66 (51 per cent) were Class A and 62 (49 per cent) Class B-D-F-R. 53.9 per cent of all infants were large for gestational age (LGA) and there were no differences between the classes of diabetics. LGA infants occurred with equal frequency in those diabetic patients with pregnancy-induced or chronic hypertension. Congenital anomalies occurred in 9.7 per cent with 11/12 in Class A, B, or C. Major neonatal morbidity included: 1) hypoglycemia: two (3 per cent) Class A and 21 (32.8 per cent) insulin-dependent mothers (P less than 0.01); and 2) respiratory distress syndrome: seven (5.3 per cent) and all were in classes B-F (P less than 0.05). Modern management of diabetes in pregnancy has, for unknown reasons, increased the incidence of LGA infants.

摘要

对128例合并糖尿病的妊娠（131例婴儿）进行了回顾性分析；66例（51%）为A类，62例（49%）为B - D - F - R类。所有婴儿中53.9%为大于胎龄儿（LGA），不同类型糖尿病患者之间无差异。LGA婴儿在患有妊娠高血压或慢性高血压的糖尿病患者中出现频率相同。先天性异常发生率为9.7%，其中A、B或C类中有11/12例。主要的新生儿发病情况包括：1）低血糖：2例（3%）A类和21例（32.8%）胰岛素依赖型母亲（P<0.01）；2）呼吸窘迫综合征：7例（5.3%），均为B - F类（P<0.05）。孕期糖尿病的现代管理，原因不明，增加了LGA婴儿的发生率。