一项针对职业前学生的预防抑郁症状和增强幸福感的基于学校的方案（快乐课程）：一项群组随机对照试验和实施研究的方案。

A school-based program to prevent depressive symptoms and strengthen well-being among pre-vocational students (Happy Lessons): protocol for a cluster randomized controlled trial and implementation study.

机构信息

Trimbos Institute, Netherlands Institute for Mental Health and Addiction, Utrecht, The Netherlands.

Department of Interdisciplinary Social Sciences, Utrecht University, Utrecht, The Netherlands.

出版信息

BMC Public Health. 2022 Jan 20;22(1):139. doi: 10.1186/s12889-021-12321-3.

DOI:10.1186/s12889-021-12321-3

PMID:35057774

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8772193/

Abstract

BACKGROUND

Depression is one of the leading causes of illness and disability among young people. In the Netherlands, one in twelve Dutch adolescents has experienced depression in the last 12 months. Pre-vocational students are at higher risk for elevated depressive symptoms. Effective interventions, especially for this risk group, are therefore needed to prevent the onset of depression or mitigate the adverse long-term effects of depression. The aim of this study is to examine the effectiveness and implementation of a school-based program Happy Lessons (HL), that aims to prevent depression and promote well-being among pre-vocational students.

METHODS

A cluster randomized controlled trial (RCT) with students randomized to HL or to care as usual will be conducted. Pre-vocational students in their first or second year (aged 12 to 14) will participate in the study. Subjects in both conditions will complete assessments at baseline and at 3- and 6-months follow-up. The primary outcome will be depressive symptoms using the Center for Epidemiologic Studies Depression Scale (CES-D) at 6-months follow-up. Secondary outcomes are well-being using the Warwick-Edinburgh Mental Well-Being Scale (WEMWBS) and life satisfaction (Cantril Ladder) measured at 6-months follow-up. Alongside the trial, an implementation study will be conducted to evaluate the implementation of HL, using both quantitative and qualitative methods (interviews, survey, and classroom observations).

DISCUSSION

The results from both the RCT and implementation study will contribute to the limited evidence base on effective school-based interventions for the prevention of depression and promotion of well-being among pre-vocational adolescents. In addition, insights from the implementation study will aid identifying factors relevant for optimizing the future implementation and scale-up of HL to other schools and contexts.

TRIAL REGISTRATION

This study was registered on 20 September 2021 in the Dutch Trial Register ( NL9732 ).

摘要

背景

抑郁症是导致年轻人患病和残疾的主要原因之一。在荷兰，每 12 名荷兰青少年中就有 1 人在过去 12 个月中经历过抑郁症。职业前学生患抑郁症状的风险较高。因此，需要有效的干预措施，尤其是针对这一风险群体，以预防抑郁症的发生或减轻抑郁症的不利长期影响。本研究旨在检验一种基于学校的预防职业前学生抑郁和促进其幸福感的项目“快乐课程”（HL）的有效性和实施情况。

方法

将采用整群随机对照试验（RCT），将学生随机分配到 HL 组或常规护理组。将招募第一或第二年（年龄 12-14 岁）的职业前学生参加研究。两组学生都将在基线和 3 个月及 6 个月随访时进行评估。主要结局是 6 个月随访时使用中心流行病学研究抑郁量表（CES-D）评估的抑郁症状。次要结局是使用 6 个月随访时的幸福感（华威-爱丁堡心理健康量表[WEMWBS]）和生活满意度（坎特里尔阶梯）来评估。除了试验外，还将进行一项实施研究，使用定量和定性方法（访谈、调查和课堂观察）评估 HL 的实施情况。