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《污染的代际传递》:(跨)代毒理学与(表观)遗传环境卫生学

"Passing Down Pollution": (Inter)generational Toxicology and (Epi)genetic Environmental Health.

作者信息

Lamoreaux Janelle

机构信息

School of Anthropology, University of Arizona.

出版信息

Med Anthropol Q. 2021 Dec;35(4):529-546. doi: 10.1111/maq.12679.

Abstract

Concern about the harmful health effects of industrial pollution is increasingly taking on an intergenerational dimension. In environmental health sciences such as toxicology, this has resulted in emphasizing the influence of toxic chemicals, substances, and situations across generations. Toxic relationalities are now being explored through research on gene-environment interaction, including toxicogenomics and epigenetic research through animal experiments and birth cohort studies. Based on fieldwork conducted among reproductive and developmental toxicologists working in Nanjing, China, this article shows how toxicological research both expresses and produces renewed anxieties about "passing down pollution." These toxicological accounts of intergenerational harm problematically work through overly simplistic renderings of reproduction and biological relatedness. But they also have the potential to catalyze creative understandings of toxic relationalities and responsibilities at a moment when making kin is increasingly seen as key to securing livable futures. [toxicology, environment, epigenetics, kinship, China].

摘要

对工业污染有害健康影响的担忧正日益呈现出代际层面。在毒理学等环境卫生科学领域,这导致人们强调有毒化学物质、物质及状况对几代人的影响。目前,正在通过基因 - 环境相互作用研究来探索毒性关系,包括通过动物实验和出生队列研究进行的毒理基因组学和表观遗传学研究。基于在中国南京从事生殖与发育毒理学工作的研究人员所开展的实地调查,本文展示了毒理学研究如何表达并引发了对“污染传承”的新焦虑。这些关于代际危害的毒理学描述通过对生殖和生物亲缘关系的过度简化呈现而产生了问题。但在建立亲属关系日益被视为确保宜居未来关键的当下,它们也有可能催化对毒性关系和责任的创造性理解。[毒理学、环境、表观遗传学、亲属关系、中国]

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