Al Dhafiri Mahdi, Almutairi Mohammed, Alutaibi Halal M, Aldandan Hassan R, Albshr Fatemah A, Alkhalifa Fatimah S
Department of Medicine, College of Medicine, King Faisal University, Al-Ahsa, SAU.
College of Medicine, King Faisal University, Al-Ahsa, SAU.
Cureus. 2021 Dec 20;13(12):e20542. doi: 10.7759/cureus.20542. eCollection 2021 Dec.
Introduction Kligman's formula is a topical triple combination consisting of hydroquinone, tretinoin, and topical corticosteroid. It has recently become widely popular among the general population for different purposes. Its improper use can lead to unsatisfactory results and unpleasant side effects. Aim This study aimed to assess the attitude, satisfaction, and complications related to topical usage of Kligman's formula among the general population in Saudi Arabia. Materials and methods A cross-sectional study was conducted among the general population of Saudi Arabia. A self-administered questionnaire was distributed among the targeted population using an online survey. The questionnaire includes socio-demographic characteristics, assessment of attitude, and satisfaction in using Kligman's formula. Data were tabulated and cleaned, and all statistical analyses were performed. Results A total of 292 participants met the inclusion criteria (26 males vs. 266 females) with a mean age of 26.9 (SD 7.71) years. Nearly 40% of participants showed a positive attitude in using Kligman's formula, while 46.9% were satisfied with using it. The most common reason for using Kligman's formula was to lighten the skin (55.8%), while skin redness was the most commonly reported adverse effect. Factors associated with increased attitude and satisfaction were using Kligman's formula based on a doctor's prescription and regular follow-up with a dermatologist. Conclusion The general population showed an improper attitude toward using Kligman's formula. However, a better attitude and satisfaction rate can be seen among those using Kligman's formula with prescription and those who regularly visit a dermatologist.
引言
克林曼配方是一种由对苯二酚、维甲酸和外用皮质类固醇组成的外用三联组合。最近，它因不同目的在普通人群中广泛流行。其不当使用可能导致不尽人意的结果和不良副作用。
目的
本研究旨在评估沙特阿拉伯普通人群中与克林曼配方外用相关的态度、满意度和并发症。
材料与方法
对沙特阿拉伯普通人群进行了一项横断面研究。通过在线调查向目标人群发放了一份自填式问卷。问卷包括社会人口学特征、对使用克林曼配方的态度评估以及满意度。数据进行了制表和清理，并进行了所有统计分析。
结果
共有292名参与者符合纳入标准（26名男性对266名女性），平均年龄为26.9岁（标准差7.71）。近40%的参与者对使用克林曼配方持积极态度，而46.9%的人对使用它感到满意。使用克林曼配方最常见的原因是美白皮肤（55.8%），而皮肤发红是最常报告的不良反应。与态度和满意度增加相关的因素是根据医生处方使用克林曼配方以及定期随访皮肤科医生。
结论
普通人群对使用克林曼配方的态度不当。然而，在那些按处方使用克林曼配方的人和定期看皮肤科医生的人中，可以看到更好的态度和满意度。
