Department of Dermatology, University Hospital Joseph Raseta Befelatanana, Antananarivo, Madagascar.
Biomed Res Int. 2017;2017:9637083. doi: 10.1155/2017/9637083. Epub 2017 Aug 21.
This cross-sectional study was conducted in Antananarivo, Madagascar, from June to September 2012. We aim to evaluate the misuse of TC on the face for cosmetic purpose and the adverse effects due to its application. A questionnaire-based analysis was done among females who use topical corticosteroids on the face for cosmetic purpose. Of the 770 women questioned, 384 (49,8%) used topical corticosteroids for cosmetic purpose whose mean age was 38 years (range 16-73 years). Two hundred and sixty-one females (68%) used TC combined with handcrafted cosmetics, and 123 (32%) used TC alone. "Pandalao," which contains salicylic acid, peppermint oil, lanolin, powder of Juanes de Vigo (mercury powder), and Vaseline, is the most handcrafted cosmetic combined with TC in our study (used by 29,4% respondents). Only one (0,26%) had obtained the TC by physician's prescription, 234 (61%) from cosmetic retailers, 92 (23%) directly from local pharmacies, 49 (12%) from beauticians, and 15 (4%) from unspecified sources. Lightening of skin color was the main reason for using TC in 44,8% of respondents in the absence of any primary dermatosis. Pigmentation disorders (63,2%) and cutaneous atrophy (52,1%) were the most adverse effects noted.
本横断面研究于 2012 年 6 月至 9 月在马达加斯加首都塔那那利佛进行。我们旨在评估将 TC 用于面部美容的不当使用情况及其应用所致的不良反应。我们对面部使用外用皮质类固醇进行美容的女性进行了基于问卷调查的分析。在接受调查的 770 名女性中,有 384 名(49.8%)因美容目的而使用外用皮质类固醇,其平均年龄为 38 岁(范围 16-73 岁)。261 名女性(68%)将 TC 与手工化妆品合用,123 名(32%)单独使用 TC。在我们的研究中,与 TC 合用的最常见手工化妆品是含有水杨酸、薄荷油、羊毛脂、Juanes de Vigo(汞粉)和凡士林的“Pandalao”(29.4%的受访者使用)。仅有 1 名(0.26%)是通过医生处方获得 TC,234 名(61%)是从化妆品零售商处获得,92 名(23%)是直接从当地药店获得,49 名(12%)是从美容师处获得,15 名(4%)是从不明来源获得。在没有任何原发性皮肤病的情况下,44.8%的受访者使用 TC 的主要原因是使肤色变浅。色素紊乱(63.2%)和皮肤萎缩(52.1%)是最常见的不良反应。