Wound & Burn Healing Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Health and Medical Education, Tehran, Iran.
Seizure. 2021 Mar;86:16-18. doi: 10.1016/j.seizure.2021.01.009. Epub 2021 Jan 23.
The aim of the current study was to investigate whether seizure is among the presenting manifestations of COVID-19.
All patients referred to emergency rooms anywhere in Iran between 12 and 25 April 2020 and who were sufficiently ill to require hospital admission with COVID-19, confirmed by a positive COVID-19 test, were studied. Data on the presenting manifestations were collected.
Of 5872 people, who were admitted to hospitals in Iran with COVID-19 during the study period, 45 came to the emergency room with seizures. This makes seizure as the presenting manifestation of COVID-19 in 0.8 % of all patients with a severe illness. 93 % of the patients were 15 years of age and older. Four of the individuals presenting with seizures (9%) had a past history of epilepsy. Fifteen of these individuals (33 %) had other chronic medical conditions (e.g., cancer, diabetes mellitus, heart disease, etc.).
This case series provides evidence that seizures are among the presenting manifestations of COVID-19 in 0.8 % of the patients who are admitted to hospital due to a severe illness.
本研究旨在探讨癫痫发作是否为 COVID-19 的首发表现之一。
研究纳入 2020 年 4 月 12 日至 25 日期间在伊朗各地急诊就诊且因 COVID-19 而病情严重需要住院治疗（通过 COVID-19 阳性检测结果确诊）的所有患者。收集患者的首发表现数据。
在研究期间，因 COVID-19 入住伊朗医院的 5872 例患者中，有 45 例因癫痫发作就诊于急诊。这使得癫痫发作成为 COVID-19 所有重症患者的 0.8%的首发表现。93%的患者年龄在 15 岁及以上。其中 4 例（9%）癫痫发作患者有癫痫病史。其中 15 例（33%）有其他慢性疾病（如癌症、糖尿病、心脏病等）。
本病例系列提供了证据表明，癫痫发作是 COVID-19 的首发表现之一，在因重症住院的患者中占 0.8%。
