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无义抑制基因对recA、recB和recC突变的抑制作用。

Suppressibility of recA, recB, and recC mutations by nonsense suppressors.

作者信息

Templin A, Margossian L, Clark A J

出版信息

J Bacteriol. 1978 May;134(2):590-6. doi: 10.1128/jb.134.2.590-596.1978.

Abstract

Mutations in the recA, recB, and recC genes of Escherichia coli K-12 were surveyed to ascertain whether or not they are suppressed by nonsense suppressors. Several mutations which map in or near the recA gene, but have not been called recA mutations, were also surveyed. An amber recB mutation, recB156, and an amber recC mutation, recC155, were isolated. One recB mutation, recB95, and four recC mutations, recC22, recC38, recC82, and recC83, were found to be suppressed by a UGA suppressor. In addition to the previously isolated amber recA mutation recA99, two other recA mutations, recA52 and recA123, were found to be suppressed by amber suppressor supD32 but not by supE44.

摘要

对大肠杆菌K-12的recA、recB和recC基因中的突变进行了研究,以确定它们是否被无义抑制基因抑制。还研究了几个位于recA基因内部或附近但未被称为recA突变的突变。分离出了一个琥珀型recB突变recB156和一个琥珀型recC突变recC155。发现一个recB突变recB95和四个recC突变recC22、recC38、recC82和recC83被一个UGA抑制基因抑制。除了之前分离出的琥珀型recA突变recA99外,还发现另外两个recA突变recA52和recA123被琥珀型抑制基因supD32抑制,但不被supE44抑制。

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