Department of Medicine, Academic Medical Center, University of Amsterdam, Meibergdreef 9, NL-1105-AZ Amsterdam, The Netherlands.
Europace. 2011 Jan;13(1):14-22. doi: 10.1093/europace/euq409. Epub 2010 Nov 17.
The carotid sinus syndrome and carotid sinus hypersensitivity (CSH) are closely related disorders. The first is characterized by syncope triggered by manipulation of the carotid sinus in daily life (e.g. shaving). According to the current European Society of Cardiology guidelines, CSH is diagnosed when carotid sinus massage elicits ≥3 s asystole, a fall in systolic blood pressure of ≥50 mmHg, or both, with symptoms. The question is, however, whether symptoms can be expected when these criteria are met. Although they are widely accepted, we will show that their basis is primarily in arbitrary clinical observations and that in the original publications the link between classification and clinical symptoms was often dubious. The current criteria for CSH are thus too sensitive, explaining the reported high prevalence of CSH in the general older population. The review will conclude with suggesting a stricter set of criteria for CSH that should be evaluated in future studies.
颈动脉窦综合征和颈动脉窦高敏性（CSH）是密切相关的疾病。前者的特征是日常生活中颈动脉窦受到刺激时发生晕厥（例如刮胡子）。根据目前的欧洲心脏病学会指南，当颈动脉窦按摩引起≥3 秒的窦性停搏、收缩压下降≥50mmHg 或两者兼有并伴有症状时，即可诊断为 CSH。然而，问题是在满足这些标准时是否可以预期出现症状。尽管这些标准被广泛接受，但我们将表明，其基础主要是任意的临床观察，并且在原始出版物中，分类与临床症状之间的联系常常是可疑的。因此，目前的 CSH 标准过于敏感，这解释了在一般老年人群中报告的 CSH 高患病率。该综述将以建议一套更严格的 CSH 标准结束，这些标准应在未来的研究中进行评估。
