Jasti V Ramanamma Children's Eye Care Centre, L.V.Prasad Eye Institute, Hyderabad, India.
The Children's Hospital at Westmead, Sydney, Australia.
Indian J Ophthalmol. 2022 Feb;70(2):386-395. doi: 10.4103/ijo.IJO_1129_21.
This review summarizes the results and interpretations of studies pertaining to the long-standing debate regarding the timing of surgery in infantile esotropia, more recently referred to as essential infantile esotropia. A systematic search of studies from the year 2000 onward pertaining to the timing of surgery in infantile esotropia as listed in PubMed, Google Scholar, and the Cochrane database was performed. Appropriate cross-references from the articles were also included. Data collected included demographics, presentation, time of surgery, complications, and outcomes. Very early surgery, that is, within 6 months of the onset of infantile esotropia, offers significant advantages in terms of the quality of stereopsis and binocular vision as well as promoting the development of cortical visual processing, thereby benefiting cortical development in human infants. However, the postoperative alignment was not found to be significantly different in the very early, early, or late surgery groups. The reduction in the incidence of manifest dissociated vertical deviation postoperatively in the very early surgery group also showed measurable benefits. The results of this recent literature review demonstrated that very early surgery, within 6 months of misalignment, showed demonstrable benefits in essential infantile esotropia.
这篇综述总结了有关婴幼儿内斜视手术时机的长期争议的研究结果和解释，最近也被称为特发性婴幼儿内斜视。在 PubMed、Google Scholar 和 Cochrane 数据库中，对 2000 年以来有关婴幼儿内斜视手术时机的研究进行了系统检索，并纳入了文章中的适当交叉引用。收集的数据包括人口统计学、表现、手术时间、并发症和结果。早期手术，即发病后 6 个月内，在立体视和双眼视觉质量以及促进皮质视觉处理发展方面具有显著优势，从而有利于人类婴儿的皮质发育。然而，在早期手术组中，并未发现早期、晚期手术组的术后眼位差异具有统计学意义。在早期手术组中，术后显性垂直分离偏差的发生率降低也显示出了可衡量的益处。最近的文献综述结果表明，发病后 6 个月内的早期手术，在特发性婴幼儿内斜视中具有明显的益处。
