Wijaksono Whendy, Koesoemoprodjo Winariani
Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
Department of Pulmonology and Respiratory Medicine, Faculty of Medicine, Universitas Airlangga - Dr. Soetomo General Academic Hospital, Surabaya, Indonesia.
Int J Surg Case Rep. 2022 Feb;91:106800. doi: 10.1016/j.ijscr.2022.106800. Epub 2022 Jan 26.
Patients with hemorrhagic pleural effusion who live in tuberculosis endemic areas are recommended to perform adenosine deaminase (ADA) test.
A Javanese 22-year-old male complained of shortness of breath and cough with phlegm for 1 week, and worsened 3 days before being admitted to the hospital. The X-ray results showed pleural effusion, and hemorrhagic pleural effusion examination showed an increase in lymphocytes (60.2%), lactate dehydrogenase/LDH (2624 U/L), and cell count (4584 cells/mm), and the ADA test obtained 49 IU/L. The water-sealed drainage (WSD) was installed and first-line anti-tuberculosis drug (ATD) was given for 1 month. After showing improvement in the first month, the first-line ATD was continued until 6 months.
Patients with hemorrhage pleural effusion who live in tuberculosis endemic areas are recommended to perform differential diagnosis of hemorrhage pleural effusion and pulmonary tuberculosis. The use of the first-line ATD in hemorrhagic pleural effusion and pulmonary tuberculosis needs to be evaluated in the first month to detect improvement, otherwise, the medication is stopped and other investigations are carried out.
Successful management of hemorrhagic pleural effusion and pulmonary tuberculosis depends on early diagnosis.
建议生活在结核病流行地区的出血性胸腔积液患者进行腺苷脱氨酶(ADA)检测。
一名22岁的爪哇男性,主诉呼吸急促和咳痰1周,入院前3天症状加重。X线检查结果显示胸腔积液,出血性胸腔积液检查显示淋巴细胞增多(60.2%)、乳酸脱氢酶/LDH(2624 U/L)和细胞计数(4584个细胞/mm),ADA检测结果为49 IU/L。进行了胸腔闭式引流(WSD),并给予一线抗结核药物(ATD)治疗1个月。在第一个月症状改善后,继续使用一线抗结核药物直至6个月。
建议生活在结核病流行地区的出血性胸腔积液患者对出血性胸腔积液和肺结核进行鉴别诊断。对于出血性胸腔积液和肺结核患者,需在第一个月评估一线抗结核药物的使用效果以检测病情是否改善,否则停药并进行其他检查。
成功治疗出血性胸腔积液和肺结核取决于早期诊断。