Smith J A
J Urol. 1986 Jan;135(1):55-7. doi: 10.1016/s0022-5347(17)45515-7.
In a controlled setting a neodymium:YAG laser is capable of producing a transmural coagulation of the bladder wall without perforation. A total of 21 patients with known muscle-invading bladder cancer underwent treatment with transurethral endoscopic application of neodymium:YAG laser energy. One patient suffered a sigmoid colon perforation that possibly was treatment-related but no other complications were observed. Four of 5 patients with clinical stage B1 and 3 of 6 with stage B2 lesions have had normal post-treatment biopsies. Local tumor control has been achieved in only 1 of 4 patients with a clinical stage C tumor and none of 6 with metastatic cancer, although palliative debulking was accomplished.
在可控环境下，钕：钇铝石榴石激光能够在不造成穿孔的情况下使膀胱壁产生透壁性凝固。共有21例已知有肌肉浸润性膀胱癌的患者接受了经尿道内镜下钕：钇铝石榴石激光能量治疗。1例患者出现乙状结肠穿孔，这可能与治疗有关，但未观察到其他并发症。5例临床分期为B1的患者中有4例，6例B2期病变患者中有3例治疗后活检结果正常。4例临床分期为C期的肿瘤患者中只有1例实现了局部肿瘤控制，6例转移性癌患者均未实现，尽管进行了姑息性减瘤手术。
