Johnson D E
Department of Urology, University of Texas M. D. Anderson Cancer Center, Houston 77030.
Lasers Surg Med. 1994;14(3):213-8. doi: 10.1002/lsm.1900140303.
This is the first North American report describing the use of the holmium:YAG (Ho:YAG) laser to treat patients with superficial bladder carcinoma. Fifteen patients, with a total of 52 recurrent superficial bladder tumors, underwent endoscopic laser photoablation of their lesions. No intraoperative or delayed complications occurred. At follow-up cystoscopy performed 3 months after lasing, four patients (27%) were without disease; eight patients (53%) had out-of-field recurrences; and three patients (20%) were classified as having in-field recurrences. We conclude that using the Ho:YAG for endoscopic treatment of patients with superficial bladder tumors is both feasible and clinically useful and that the lack of perceived pain or discomfort during lasing, as well as the lack of need for an in-dwelling urethral catheter, makes it advantageous for selected patients over conventional electroresection techniques.
这是首份描述使用钬激光（Ho:YAG）治疗浅表性膀胱癌患者的北美报告。15名患者共有52处复发性浅表膀胱肿瘤，接受了内镜激光光凝消融其病变。未发生术中或延迟并发症。在激光治疗3个月后进行的随访膀胱镜检查中，4名患者（27%）无疾病；8名患者（53%）有野外复发；3名患者（20%）被归类为有野内复发。我们得出结论，使用Ho:YAG内镜治疗浅表膀胱肿瘤患者是可行且具有临床实用性的，并且激光治疗期间无明显疼痛或不适，以及无需留置尿道导管，这使其对于选定患者而言优于传统电切技术。
