Division of Clinical Paediatrics, Department of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Astrid Lindgren Children's Hospital, Karolinska University Hospital, Stockholm, Sweden.
Cell Rep Med. 2022 Jan 18;3(1):100490. doi: 10.1016/j.xcrm.2021.100490.
Neurofilament light (NFL) is a promising circulating biomarker in preeclampsia and COVID-19, even without evident neurological complications. Several pathways might contribute to the elevated serum NFL levels seen in both pathologies. Future studies will determine whether NFL is a long COVID marker and delineate NFL's role in COVID-19-associated preeclampsia.
神经丝轻链(NFL)是子痫前期和 COVID-19 中很有前途的循环生物标志物,即使没有明显的神经并发症也是如此。几种途径可能导致这两种病理情况下血清 NFL 水平升高。未来的研究将确定 NFL 是否是长 COVID 的标志物,并阐明其在 COVID-19 相关子痫前期中的作用。