Section for Clinical Cancer Research, Oslo University Hospital, Oslo, Norway.
Faculty of Medicine, University of Oslo, Norway.
Acta Oncol. 2022 Mar;61(3):357-362. doi: 10.1080/0284186X.2021.2006775. Epub 2022 Feb 1.
In a cross-sectional observational study to explore long-term satisfaction with treatment among men who had undergone radical prostatectomy (RP) or definitive pelvic radiotherapy (RT) for prostate cancer (PCa).
After mean 7 years from therapy (range: 6-8), 431 PCa-survivors (RP: = 313, RT: = 118) completed a mailed questionnaire assessing persistent treatment-related adverse effects (AEs) (Expanded Prostate cancer Index Composite [EPIC-26]) and seven Quality indicators describing satisfaction with the health care service following a most often general practitioner (GP)-led follow-up plan. A logistic regression model evaluated the associations between long-term satisfaction and treatment modality, age, the seven satisfaction-related Quality indicators, and persistent AEs. The significance level was set at < .05.
Four of five (81%) PCa-survivors reported long-term satisfaction with their treatment. In a multivariable model, satisfaction was positively associated with sufficient information about treatment and AEs, patient-perceived sufficient cooperation between the hospital and the GP and sufficient follow-up of AEs (ref.: insufficient). Age ≥70 years (ref.: <70) and a rising summary score within the EPIC-26 sexual domain additionally increased long-term satisfaction. The treatment modality itself (RP RT) did not significantly impact on satisfaction.
The majority of curatively treated PCa-survivors are satisfied with their treatment more than 5 years after primary therapy. Sufficient information, improved cooperation between the hospital specialists and the responsible GP and optimized follow-up of AEs may further increase long-term satisfaction among prostatectomized and irradiated PCa-survivors.
在一项横断面观察性研究中，探索接受根治性前列腺切除术（RP）或根治性盆腔放疗（RT）治疗前列腺癌（PCa）的男性患者的长期治疗满意度。
在治疗后平均 7 年（范围：6-8 年），431 名 PCa 幸存者（RP：=313，RT：=118）完成了一份邮寄问卷，评估了持续存在的与治疗相关的不良事件（AE）（扩展前列腺癌指数综合评分[EPIC-26]）和七个描述在最常见的全科医生（GP）主导的随访计划后对医疗服务满意度的质量指标。逻辑回归模型评估了长期满意度与治疗方式、年龄、七个与满意度相关的质量指标以及持续存在的 AE 之间的关联。显著性水平设定为<.05。
五分之四（81%）的 PCa 幸存者报告对他们的治疗长期满意。在多变量模型中，满意度与关于治疗和 AE 的充分信息、患者感知的医院和 GP 之间充分的合作以及 AE 的充分随访（参考：不足）呈正相关。年龄≥70 岁（参考：<70 岁）和 EPIC-26 性领域的总分升高也增加了长期满意度。治疗方式本身（RP 与 RT）对满意度没有显著影响。
在初次治疗后 5 年以上，大多数接受根治性治疗的 PCa 幸存者对其治疗满意。提供充分的信息、改善医院专家与负责 GP 之间的合作以及优化 AE 的随访可能会进一步提高前列腺切除术和放疗后的 PCa 幸存者的长期满意度。
