Department of Dermatology, Mehektagul Dermaclinic, New Delhi, India.
Department of Pharmacology, Dr. DY Patil Medical College, Navi Mumbai, India.
J Cosmet Dermatol. 2022 Apr;21(4):1393-1401. doi: 10.1111/jocd.14815. Epub 2022 Feb 14.
Cellulite is a common dermatological condition with a female preponderance, affecting up to 90% post-pubertal females. It is characterized with dimpling and denting of the skin surface, giving it a Peau d'orange appearance. Once considered to be a benign physiological isolated skin condition of only an esthetic concern, cellulite is now considered a pathological entity with systemic associations and a negative psychological impact on patients.
The objective of this article was to discuss etiology, pathophysiology, and treatment of cellulite.
Literature was screened to retrieve articles from PubMed/Medline and Google Scholar and related websites. Cross-references from the relevant articles were also considered for review. Review articles, clinical studies, systematic reviews, meta-analysis, and relevant information from selected websites were included.
Several treatment options from lifestyle modifications and topical cosmetic therapies to energy-based devices have been studied for its treatment. However, treatment remains a challenge despite many new modalities in the armamentarium. Laser and light therapies along with radiofrequency are useful treatment options with good safety profile. Acoustic wave therapy, subcision, and 1440-nm Nd:YAG minimally invasive laser are beneficial in cellulite reduction.
Methodological differences in the trials conducted make it difficult to compare different treatment modalities.
Overall, treatment needs to be individualized based on the patient characteristics and severity of the condition. A combination of treatments is often required in most patients for reducing cellulite.
脂肪团是一种常见的皮肤病，女性患病率较高，多达 90%的青春期后女性受到影响。其特征为皮肤表面出现凹痕和凹陷，呈现出“桔皮样”外观。脂肪团曾经被认为是一种良性的孤立性皮肤生理状况，仅与美观有关，但现在被认为是一种具有系统性关联的病理性实体，对患者的心理产生负面影响。
本文旨在讨论脂肪团的病因、发病机制和治疗方法。
通过检索 PubMed/Medline 和 Google Scholar 以及相关网站上的文章，筛选文献。还考虑了相关文章的交叉引用进行综述。纳入了综述文章、临床研究、系统评价、荟萃分析以及从选定网站获得的相关信息。
已经研究了多种治疗选择，包括生活方式改变和局部美容疗法，以及能量设备。然而，尽管有许多新的治疗方法，治疗仍然是一个挑战。激光和光疗以及射频是具有良好安全性的有用治疗选择。声波疗法、皮下分离术和 1440nm Nd:YAG 微创激光对减少脂肪团有效。
临床试验中的方法学差异使得难以比较不同的治疗方法。
总体而言，需要根据患者的特征和病情严重程度个体化治疗。大多数患者通常需要联合治疗来减少脂肪团。
