Rosenpark Research, Wilhelminenstraße 13, 64283, Darmstadt, Germany.
Sadick Dermatology, 911 Park Avenue, New York, NY, USA.
Am J Clin Dermatol. 2015 Aug;16(4):243-256. doi: 10.1007/s40257-015-0129-5.
Cellulite is a multifactorial condition that is present in 80-90 % of post-pubertal women. Despite its high prevalence, it remains a major cosmetic concern for women. A wide range of products and treatments for cellulite reduction is available; however, no systematic review has been performed so far to evaluate the efficacy of the available treatment options for cellulite.
The objective of this review is to provide a systematic evaluation of the scientific evidence of the efficacy of treatments for cellulite reduction.
This systematic review followed the PRISMA guidelines for reporting systematic reviews and meta-analyses. Only original articles in English or German reporting data on the efficacy of cellulite treatments from in vivo human studies were considered. In total, 67 articles were analyzed for the following information: therapy, presence of a control group, randomization, blinding, sample size, description of statistical methods, results, and level of evidence.
Most of the evaluated studies, including laser- and light-based modalities, radiofrequency, and others had important methodological flaws; some did not use cellulite severity as an endpoint or did not provide sufficient statistical analyses. Of the 67 studies analyzed in this review, only 19 were placebo-controlled studies with randomization. Some evidence for potential benefit was only seen for acoustic wave therapy (AWT) and the 1440 nm Nd:YAG minimally invasive laser.
This article provides a systematic evaluation of the scientific evidence of the efficacy of treatment for cellulite reduction. No clear evidence of good efficacy could be identified in any of the evaluated cellulite treatments.
脂肪团是一种多因素的病症，存在于 80-90%的青春期后女性中。尽管它很普遍，但它仍然是女性的主要美容关注点。有广泛的产品和治疗方法可用于减少脂肪团；然而，到目前为止，还没有进行系统的综述来评估现有的脂肪团治疗选择的疗效。
本综述的目的是对减少脂肪团的治疗效果的科学证据进行系统评价。
本系统评价遵循 PRISMA 指南进行报告系统评价和荟萃分析。仅考虑了以英文或德文发表的关于体内人类研究中脂肪团治疗效果的数据的原始文章。总共分析了 67 篇文章，以获取以下信息：治疗方法、是否存在对照组、随机分组、盲法、样本量、统计方法描述、结果和证据水平。
大多数评估的研究，包括激光和光基模式、射频等，都存在重要的方法学缺陷；有些没有将脂肪团严重程度作为终点，也没有提供足够的统计分析。在本综述中分析的 67 篇研究中，只有 19 篇是有安慰剂对照和随机分组的研究。一些证据表明声能波治疗（AWT）和 1440nmNd:YAG 微创激光可能有潜在的益处。
本文对减少脂肪团的治疗效果的科学证据进行了系统评价。在评估的任何脂肪团治疗方法中，都没有明确的良好疗效证据。
