Kamaruzaman Intan Noor Aina, Ng Kian Yiing, Hamdan Ruhil Hayati, Shaharulnizim Nurshahirah, Zalati Che Wan Salma Che Wan, Mohamed Maizan, Nordin Muhammad Luqman, Rajdi Nur Zul Izzati Mohd, Abu-Bakar Luqman, Reduan Mohd Farhan Hanif
Faculty of Veterinary Medicine, Universiti Malaysia Kelantan, Kelantan, Malaysia.
J Adv Vet Anim Res. 2021 Nov 1;8(4):576-580. doi: 10.5455/javar.2021.h547. eCollection 2021 Dec.
The case study describes the cause of an increase in mortality rates among 35-day-old broilers that developed respiratory distress and bloody diarrhea on a farm in Malaysia.
The organ samples were subjected to laboratory testing and postmortem inspection. (E.) and (M.) were detected using bacterial isolation and molecular diagnostics using polymerase chain reaction.
Chickens with the infection had widespread fibrin buildup in several organs and hemorrhages on the duodenal mucosa. Additional histology and laboratory analysis of organ samples revealed infection with , , and enteric spp., all of which are consistent with complex chronic respiratory disease (CCRD) associated with coccidiosis. Tylosin tartrate 20% (w/w) (2.5 gm/l) was prescribed for 1 week along with a combination of the broad-spectrum bacteriostatic drug streptomycin (25 mg/kg) and coccidiostat (2 gm/5 l).
CCRD and coccidiosis are both infectious diseases that can infect chicken flocks, resulting in production losses and carcass quality degradation. Early disease detection and proper treatment should be provided promptly, and tight farm biosecurity should be implemented to prevent chicken mortality on the farm, as was achieved successfully.
本案例研究描述了马来西亚一个农场中35日龄肉鸡出现呼吸窘迫和血性腹泻后死亡率上升的原因。
对器官样本进行实验室检测和尸检。使用细菌分离和聚合酶链反应进行分子诊断检测（E.）和（M.）。
感染鸡在多个器官有广泛的纤维蛋白沉积，十二指肠黏膜有出血。对器官样本进行的额外组织学和实验室分析显示感染了、、和肠道 spp.，所有这些都与与球虫病相关的复杂慢性呼吸道疾病（CCRD）一致。开了20%（w/w）的泰乐菌素（2.5克/升），连用1周，同时使用广谱抑菌药物链霉素（25毫克/千克）和抗球虫药（2克/5升）的组合。
CCRD和球虫病都是可感染鸡群的传染病，会导致生产损失和胴体质量下降。应及时进行早期疾病检测和适当治疗，并实施严格的农场生物安全措施以防止农场鸡只死亡，本案例已成功实现这一点。
