基于网络的应用程序“QUiPP v.2”可用于预测有症状的女性早产，但尚未准备好在全球范围内用于临床：关于开发、验证和使用的十点思考。
The web-based application "QUiPP v.2" for the prediction of preterm birth in symptomatic women is not yet ready for worldwide clinical use: ten reflections on development, validation and use.
机构信息
Obstetrics and Gynaecology, Ghent University Hospital, Corneel Heymanslaan 10, 9000, Ghent, Belgium.
Department of Internal Medicine and Paediatrics, Renal Division, Ghent University, Ghent, Belgium.
出版信息
Arch Gynecol Obstet. 2022 Aug;306(2):571-575. doi: 10.1007/s00404-022-06418-2. Epub 2022 Feb 2.
PURPOSE
In this correspondence, we highlight general and domain-specific caveats in the development and validation of prediction models.
METHODS
Development and use of the "QUiPP" application, a tool for preterm birth prediction which is supported by the United Kingdom National Health Service, is scrutinised and commented on.
RESULTS
We highlight and elaborate ten points which may be perceived to be unclear or potentially misleading.
CONCLUSION
While the QUiPP application has high potential, it lacks transparency (on certain aspects related to model development) and proper validation. This precludes transportability to settings with other treatment policies and to other countries where the app has been made publicly available.
目的
在本通信中，我们强调了在预测模型的开发和验证中存在的一般和特定领域的注意事项。
方法
我们仔细审查和评论了“QUiPP”应用程序的开发和使用情况，该应用程序是英国国民保健服务系统支持的一种早产预测工具。
结果
我们强调并详细说明了可能被认为不清楚或具有潜在误导性的十点。
结论
虽然 QUiPP 应用程序具有很大的潜力，但它缺乏透明度（在与模型开发相关的某些方面）和适当的验证。这使得它无法在具有其他治疗政策的环境中以及在该应用程序已公开提供的其他国家中进行移植。
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