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巴西低腰背痛、类风湿关节炎、骨关节炎和痛风的负担及其各自的归因危险因素:GBD 2017 研究结果。

The burden of low back pain, rheumatoid arthritis, osteoarthritis, and gout and their respective attributable risk factors in Brazil: results of the GBD 2017 study.

机构信息

Universidade Federal de Minas Gerais, Faculdade de Medicina, Programa de Pós-Graduação em Saúde Pública, Belo Horizonte, MG, Brasil.

Universidade Federal de Minas Gerais, Núcleo de Estudos Saúde e Trabalho, Belo Horizonte, MG, Brasil.

出版信息

Rev Soc Bras Med Trop. 2022 Jan 28;55(suppl 1):e0285. doi: 10.1590/0037-8682-0285-2021. eCollection 2022.

DOI:10.1590/0037-8682-0285-2021
PMID:35107535
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9009435/
Abstract

INTRODUCTION

Musculoskeletal (MSK) disorders are a major cause of disability worldwide. Different modifiable risk factors are associated to these disorders. The objective of this study was to analyze the burden of low back pain (LBP), rheumatoid arthritis (RA), osteoarthritis (OA), and gout, attributable to risk factors, in 2017.

METHODS

The burden of LBP, RA, OA, and gout, and attributable risk factors were analyzed using data extracted from the Global Burden of Disease (GBD) Brasil-2017 study. Descriptive analysis was conducted to compare disability-adjusted life years (DALY) rates between sexes and age groups (15-49 and 50-69 years), in 2017.

RESULTS

The highest rates of DALY due to LBP were attributed to occupational ergonomic factors in the 15-49-year group, regardless of sex and males aged 50-69 years, whereas smoking was the major contributor in the 50-69-year female group. RA-related DALY rates were attributed to smoking and were higher among women aged 50-69 years. High body mass index (BMI) was the most relevant risk factor for the burden of OA, with higher rates detected in the 50-69-year group, and it was the most significant risk factor for DALY rate attributed to gout, regardless of sex or age group.

CONCLUSIONS

Occupational surveillance measures are indicated to prevent LBP. Actions to decrease smoking and overweight, and the surveillance of weight gain are warranted to decrease the burden of LBP, RA and OA, and gout, respectively. These actions will be more effective if age and sex differentials are considered in planning.

摘要

简介

肌肉骨骼(MSK)疾病是全球残疾的主要原因。不同的可改变的危险因素与这些疾病有关。本研究的目的是分析 2017 年与风险因素相关的腰痛(LBP)、类风湿关节炎(RA)、骨关节炎(OA)和痛风的负担。

方法

使用从全球疾病负担(GBD)巴西-2017 研究中提取的数据,分析 LBP、RA、OA 和痛风的负担以及归因于危险因素的情况。对 2017 年不同性别和年龄组(15-49 岁和 50-69 岁)的残疾调整生命年(DALY)率进行描述性分析。

结果

15-49 岁组中,由于职业工效学因素导致的 LBP 导致的 DALY 率最高,无论性别如何,50-69 岁的男性也是如此,而 50-69 岁的女性则主要归因于吸烟。RA 相关的 DALY 率归因于吸烟,50-69 岁的女性发生率更高。高身体质量指数(BMI)是 OA 负担的最重要危险因素,50-69 岁年龄组的发生率更高,而不论性别或年龄组,BMI 都是导致痛风 DALY 率的最重要危险因素。

结论

需要采取职业监测措施来预防 LBP。应采取行动减少吸烟和超重,并监测体重增加,以分别降低 LBP、RA 和 OA 以及痛风的负担。如果在规划中考虑到年龄和性别差异,这些措施将更有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65ce/9009435/1ff70f098b23/1678-9849-rsbmt-55-s01-e0285-2021-gf2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65ce/9009435/298c2e6f455f/1678-9849-rsbmt-55-s01-e0285-2021-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65ce/9009435/1ff70f098b23/1678-9849-rsbmt-55-s01-e0285-2021-gf2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65ce/9009435/298c2e6f455f/1678-9849-rsbmt-55-s01-e0285-2021-gf1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/65ce/9009435/1ff70f098b23/1678-9849-rsbmt-55-s01-e0285-2021-gf2.jpg

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