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2019冠状病毒病大流行期间结缔组织病相关间质性肺疾病患者的管理

Management of Patients with Connective Tissue Disease-associated Interstitial Lung Diseases During the COVID-19 Pandemic.

作者信息

Gunduz Gurkan Canan, Karadogan Dilek, Ufuk Furkan, Cure Osman, Altinisik Goksel

机构信息

Department of Chest Diseases, Süreyyapaşa Chest Diseases and Thoracic Surgery Training and Research Hospital, İstanbul, Turkey.

Department of Chest Diseases, Recep Tayyip Erdogan University, School of Medicine, Rize, Turkey.

出版信息

Turk Thorac J. 2021 Jul;22(4):346-352. doi: 10.5152/TurkThoracJ.2021.20172.

Abstract

The novel coronavirus disease (COVID-19) is similar to connective tissue disease-associated interstitial lung diseases (CTD-ILD) in many aspects. However, patients with CTD-ILD have required particular attention during the pandemic since they are at high risk due to -immunosuppressive treatments. Thus, prompt decisions for diagnosis and treatment initiation have become more important than earlier for these patients during the pandemic. Radiological perspectives have become inevitable for the differential diagnosis of this group ¬during the pandemic, particularly to obtain rapid and accurate results that allow the physicians to start treatment immediately. However, in addition to radiological images, a definitive diagnosis also requires access to extensive information regarding patient history, including characteristics of comorbidities, and clinical and serological findings. Consequently, the differential diagnosis of COVID-19 and CTD-ILD can yield accurate treatment regimens that differ greatly between the 2 diseases, and also prevent the spread of the outbreak with COVID-19 patients treated under isolation.

摘要

新型冠状病毒病(COVID-19)在许多方面与结缔组织病相关间质性肺疾病(CTD-ILD)相似。然而,CTD-ILD患者在疫情期间需要特别关注,因为他们因免疫抑制治疗而处于高风险中。因此,对于这些患者来说,在疫情期间迅速做出诊断和开始治疗的决定比以往任何时候都更加重要。在疫情期间,放射学观点对于该组疾病的鉴别诊断已变得不可或缺,特别是为了获得快速准确的结果,以便医生能够立即开始治疗。然而,除了放射学图像外,明确的诊断还需要获取有关患者病史的广泛信息,包括合并症的特征以及临床和血清学检查结果。因此,COVID-19和CTD-ILD的鉴别诊断可以得出准确的治疗方案,这两种疾病的治疗方案差异很大,同时还可以防止COVID-19患者在隔离治疗期间疫情的传播。

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Ann Rheum Dis. 2020 Aug;79(8):1007-1013. doi: 10.1136/annrheumdis-2020-217627. Epub 2020 May 22.
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Perspectives of Immune Therapy in Coronavirus Disease 2019.新型冠状病毒肺炎的免疫治疗观点。
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