Rehman Sara, Rehman Anis U, Naveed Muhammed A, Iftikhar Aamer
Radiology, Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, PAK.
Cureus. 2021 Dec 28;13(12):e20787. doi: 10.7759/cureus.20787. eCollection 2021 Dec.
CNS tuberculosis has a broad spectrum of disease patterns and a high risk of complications and mortality. We present a case of a 36-year-old man who was diagnosed with neurotuberculosis with intracranial and spinal tuberculomas, meningitis, and spondylodiscitis. The patient was a known case of sarcoidosis and was being managed on corticosteroids. His presenting complaints were headache, low-grade fever, severe backache, lower limb weakness, and one episode of altered sensorium. The initial diagnosis was based on imaging findings, which were confirmed with positive cerebrospinal fluid (CSF) culture for Mycobacterium tuberculosis. Imaging and clinicopathological correlation enables early diagnosis and treatment and prevents permanent neurological sequelae.
中枢神经系统结核具有广泛的疾病模式，且并发症和死亡率风险很高。我们报告一例36岁男性，被诊断为患有颅内和脊髓结核瘤、脑膜炎和脊椎椎间盘炎的神经结核。该患者为已知的结节病病例，正在接受糖皮质激素治疗。他的主要症状为头痛、低热、严重背痛、下肢无力以及一次意识改变发作。初步诊断基于影像学检查结果，脑脊液（CSF）结核分枝杆菌培养阳性进一步证实了诊断。影像学与临床病理的相关性有助于早期诊断和治疗，并预防永久性神经后遗症。
