al-Deeb S M, Yaqub B A, Sharif H S, Motaery K R
Department of Clinical Neurosciences, Riyadh Armed Forces Hospital, Saudi Arabia.
Clin Neurol Neurosurg. 1992;94 Suppl:S30-3. doi: 10.1016/0303-8467(92)90014-t.
Tuberculosis is still a major cause of serious illness in many parts of the world. CNS involvement has frequently been found secondary to tuberculosis elsewhere in the body, particularly the lungs. The disease manifests itself as meningitis, tuberculoma and/or spinal tuberculosis. The presence of tuberculosis elsewhere in the body favors the diagnosis although its absence does not exclude it. While tuberculous meningitis is a disease of childhood, tuberculomas and spinal tuberculosis are invariably an adult manifestation. The great majority of patients with neurotuberculosis are diagnosed and treated early because of characteristic clinical, imaging, and CSF findings. Clinical response to antituberculous therapy in all forms of neurotuberculosis is excellent if the diagnosis is made early before irreversible neurological deficit is established.
在世界许多地区，结核病仍是严重疾病的主要病因。中枢神经系统受累常继发于身体其他部位的结核病，尤其是肺部。该疾病表现为脑膜炎、结核瘤和/或脊柱结核。身体其他部位存在结核病有助于诊断，但其不存在也不能排除诊断。虽然结核性脑膜炎是一种儿童疾病，但结核瘤和脊柱结核则总是成人的表现。绝大多数神经结核病患者由于典型的临床、影像学和脑脊液检查结果而得以早期诊断和治疗。如果在出现不可逆的神经功能缺损之前早期做出诊断，所有形式的神经结核病对抗结核治疗的临床反应都很好。
