Ma Cheng-Jen, Hu Wan-Hsiang, Huang Meng-Chuan, Chiang Jy-Ming, Hsieh Pao-Shiu, Wang Huann-Sheng, Chiang Chien-Ling, Hsieh Hui-Min, Chen Chou-Chen, Wang Jaw-Yuan
Division of Colorectal Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Division of General and Digestive Surgery, Department of Surgery, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan.
Front Oncol. 2022 Jan 17;11:819742. doi: 10.3389/fonc.2021.819742. eCollection 2021.
Malnutrition and systemic inflammatory response (SIR) frequently occur in patients with colorectal cancer (CRC) and are associated with poor prognosis. Anti-inflammatory nutritional intervention is not only a way to restore the malnourished status but also modulate SIR. Nine experts, including colorectal surgeons, physicians and dieticians from 5 hospitals geographically distributed in Taiwan, attended the consensus meeting in Taiwan Society of Colon and Rectum Surgeons for a 3-round discussion and achieved the consensus based on a systematic literature review of clinical studies and published guidelines. The consensus recommends that assessment of nutritional risk and SIR should be performed before and after CRC treatment and appropriate nutritional and/or anti-inflammatory intervention should be adapted and provided accordingly.
营养不良和全身炎症反应(SIR)在结直肠癌(CRC)患者中经常出现,并与预后不良相关。抗炎营养干预不仅是恢复营养不良状态的一种方法,还能调节全身炎症反应。来自台湾5家医院的9位专家,包括结直肠外科医生、内科医生和营养师,参加了台湾结直肠外科医师学会的共识会议,进行了三轮讨论,并在对临床研究和已发表指南进行系统文献综述的基础上达成了共识。该共识建议,应在CRC治疗前后评估营养风险和全身炎症反应,并相应地采取和提供适当的营养和/或抗炎干预措施。